4 documents found, page 1 of 1
New cation sensors based on eugenol-derived azo dyes
Coelho, José R. A.; Pacheco, Ana Rita Faria; Domingues, Diogo C.; Rodrigues, Ana Rita Oliveira; Temitope, Akani A.; Coutinho, Paulo J. G.Eugenol-based azo dyes illustrate how bio-sourced compounds like eugenol can be transformed through synthetic processes into functional and colorful compounds. The main purpose of the present work was to develop new responsive colorimetric sensors for metal cations based on eugenol-derived azo compounds. The incorporation of the azo group into the eugenol framework allows for strong electronic interactions with...
Elastic liposomes containing calcium/magnesium ferrite nanoparticles coupled wi...
Pacheco, Ana Rita Faria; Barros, Ana Margarida; Amorim, Carlos O.; Amaral, Vítor S.; Coutinho, Paulo J. G.; Rodrigues, Ana Rita OliveiraThis work reports on the design, development, and characterization of novel magneto-plasmonic elastic liposomes (MPELs) of DPPC:SP80 (85:15) containing Mg0.75Ca0.25Fe2O4 nanoparticles coupled with gold nanorods, for topical application of photothermal therapy (PTT). Both magnetic and plasmonic components were characterized regarding their structural, morphological, magnetic and photothermal properties. The magn...
NIR triggered elastic liposome containing magneto-plasmonic nanoparticles for t...
Pacheco, Ana Rita Faria; Barros, Ana Margarida Macedo Veloso; Castanheira, Elisabete M. S.; Rodrigues, Ana Rita OliveiraElastic liposomes (ELs) are excellent nanocarrier for topical applications due to their ultra-deformable properties. The integration of magnetic and plasmonic nanoparticles into these Els, forming magneto-plasmonic elastic liposomes, (MPELs) is a promising approach with potential to treat topical disease conditions. The combination of both magnetic and plasmonic components in a single system maximize the cell d...
Desenvolvimento de magnetolipossomas sensíveis ao pH contendo nanopartículas ma...
Pacheco, Ana Rita FariaAs terapias convencionais do cancro apresentam ainda muitas barreiras por ultrapassar. O diagnóstico tardio e a toxicidade sistémica associados a tratamentos clássicos dificultam grandemente a terapia oncológica, diminuindo a eficácia terapêutica. Assim, é fundamental o desenvolvimento de terapias mais seguras que possibilitem o direcionamento de fármacos à região tumoral, eliminando seletivamente células anorm...