Introdução: A hérnia inguinal é um tipo de hérnia da parede abdominal e constitui a patologia cirúrgica mais comum nos cuidados de saúde primários. A infeção local e a formação de seroma ou hematoma são complicações comuns, ao contrário de complicações mais graves, como a migração da prótese ou a perfuração de órgãos adjacentes. Descrição do caso: Utente do sexo masculino, de 57 anos de idade, com múltiplos ant...
Depression is one of the main risk factors for suicide. However, little is known about the intricate relationships among depressive symptomatology in unipolar depression, suicide risk, and the characteristics of executive dysfunction in depressed patients. We compared 20 non-psychotic unipolar depressed suicide attempters to 20 matching depressed non-attempters and to 20 healthy controls to further investigate ...
Alterations in executive functioning are frequent in depressive patients. One clinical characteristic of depression is difficulty and slowness in decision-making. This study aimed to compare the performance of a group of 30 non-psychotic unipolar depressed to 30 healthy controls in a version of the Iowa Gambling Task (IGT) from the Psychology Experiment Building Language (PEBL). Significant differences between ...
Recent studies have emphasized that developmental dyslexia is a multiple-deficit disorder, in contrast to the traditional single-deficit view. In this context, cognitive profiling of children with dyslexia may be a relevant contribution to this unresolved discussion. The aim of this study was to profile 36 Portuguese children with dyslexia from the 2nd to 5th grade. Hierarchical cluster analysis was used to gro...
Specific ceramides are key regulators of cell fate, and extensive studies aimed to develop therapies based on ceramide-induced cell death. However, the mechanisms regulating ceramide cytotoxicity are not yet fully elucidated. Since ceramides also regulate growth and stress responses in yeast, we studied how different exogenous ceramides affect yeast cells. C2-phytoceramide, a soluble form of phytoceramides, the...
Background: Acetic acid is mostly known as a toxic by-product of alcoholic fermentation carried out by Saccharomyces cerevisiae, which it frequently impairs. The more recent finding that acetic acid triggers apoptotic programmed cell death (PCD) in yeast sparked an interest to develop strategies to modulate this process, to improve several biotechnological applications, but also for biomedical research. Indeed,...
A evolução humana permitiu algumas conquistas culturais, como a compet~encia aprendida formalmente para (des)codificar linguagem escrita, ato que implica um elevado grau de complexidade em termos de atividade cerebral. Apesar de variados estudos procurarem compreender os processos cognitivos e os correlatos cerebrais da leitura, impõe-se ainda a compreensão das dificuldades que muitas crianças revelam, não obst...
The aim of the present work was the phenotypic and genotypic characterization of isolates from the yeast collection of the Instituto dos Vinhos do Douro e Porto, I.P, in order to evaluate their oenological potential for use as fermentation starters in the production of high quality wines with regional character. Results showed that most of the 103 strains tested in the first screen had high fermentative capacit...