30 documents found, page 1 of 3
Overview and aspects of the european technical specification CEN/TS 19101:2022,...
Correia, João R.; Ascione, Luigi; Keller, Thomas; Mottram, Toby; Sena-Cruz, José; Paulotto, Carlo; Knippers, Jan; Pacheco, JoãoIn November 2022, the European Committee for Standardization (CEN) published the Technical Specification CEN/TS 19101:2022, “Design of Fibre-Polymer Composite Structures.” These design provisions, which follow the philosophy and partial factor format of the Eurocodes, are a milestone toward the widespread application of composite materials in civil engineering structures. This paper presents an overview and hig...
Effect of a soil biofertilizer in the functional profile of the soil microbial ...
Lima-Filho, Sonny; Pacheco, João; Ganilho, Catarina; Crespo, Rute; Andreani, Tatiana; Godinho, Mariana; Pereira, Sofia; Pereira, RuthIntroduction: The dependency on crops of products with synthetic chemical compounds, whether fertilizers or pesticides, for saving the development and yield has been a challenge to the environment, and new alternatives are being sought to change this reality. The excessive use of chemicals affects human health and soil quality. Therefore, there is a significant need to produce green compounds that are environme...
Effect of a soil biofertilizer in the functional profile of the soil microbial ...
Lima, Sonny; Pacheco, João; Ganilho, Catarina; Crespo, Rute; Andreani, Tatiana; Godinho, Mariana; Pereira, Sofia; Pereira, RuthBackground & Aim: The dependency on crops of products with chemical compounds, whether fertilizers or pesticides, for saving the development and yield has been a challenge to the environment, and new alternatives are being sought to change this reality. The excessive use of chemicals affects human health and soil quality. There is a significant need to produce green compounds that are environmentally sustainabl...
Challenging invasive fungal infections: development of innovative electrochemic...
Castanheira, Michelle; Morais, Stephanie L.; Seguro, Isabel; Santos, Marlene; Lima, Luís; Pacheco, João; Barroso, M. FátimaDespite the considerable advances in the prevention and treatment of fungal infections, invasive fungus such as Candida spp., continues to be one of the major causes of morbidity and mortality. The Global Action Fund Infections reported that, annually, more than 300 million people are infected with fungal infection, from these, about 1.5 million ends up dying. Candida albicans is the most important fungal 66 op...
Proteomics Reveals mRNA Regulation and the Action of Annexins in Thyroid Cancer
Coelho, Margarida; Capela, João; Anjo, Sandra I.; Pacheco, João; Fernandes, Margarida Sá; Amendoeira, Isabel; Jones, John G.; Raposo, LuísDifferentiated thyroid cancer is the most common malignancy of the endocrine system. Although most thyroid nodules are benign, given the high incidence of thyroid nodules in the population, it is important to understand the differences between benign and malignant thyroid cancer and the molecular alterations associated with malignancy to improve detection and signal potential diagnostic, prognostic, and therape...
RP-16 Demonstração de um Novo Modelo Avaliativo na Facultade de Medicina da Uni...
Pacheco, João; Marreiros, Ana; Nzwalo, Hipólito; Marvão, PedroIntrodução: Na educação médica, os currículos integrados tornaram-se um conceito popular que se difundiu globalmente atingindo diversas organizações de acreditação médica. Um currículo integrado pode ser descrito, por exemplo, como a integração da ética e aptidões clínicas desde o início do curso de medicina; combinar experiências clínicas e ciências básicas numa única unidade curricular; integrar a exposição c...
Thermal performance of concrete with reactive magnesium oxide as an alternative...
Forero Valencia, Javier Andres; Bravo, Miguel; Pacheco, João; Brito, Jorge de; Evangelista, LuisThis study evaluates the thermal conductivity of concrete produced with reactive magnesium oxide (MgO) as a partial replacement for cement. MgO is a viable option for the concrete industry, mainly due to its benefits in sustainability and reducing CO2 emissions compared to cement emissions. Four different MgO's produced in Australia, Canada, and Spain were used in concrete mixes as a partial replacement of ceme...
A simple electrochemical detection of atorvastatin based on disposable screen-p...
Rebelo, Patrícia; Pacheco, João; Voroshylova, Iuliia; Melo, André; Cordeiro, M. Natália D.S.; Delerue-Matos, CristinaAtorvastatin (ATV) is a statin member consumed in high quantities worldwide. In response to that, the occurrence of ATV in environmental waters has become a reality, highlighting the need of rapid and sensitive analytical devices for its monitoring. In this work, the first electrochemical molecularly imprinted polymer (MIP) sensor for the detection of ATV in water samples is presented. Computational studies wer...
Computational Modelling and Sustainable Synthesis of a Highly Selective Electro...
Rebelo, Patrícia; Pacheco, João; Voroshylova, Iuliia V.; Seguro, Isabel; Cordeiro, Maria Natália D. S.; Delerue-Matos, CristinaA novel molecularly imprinted polymer (MIP) has been developed based on a simple and sustainable strategy for the selective determination of citalopram (CTL) using screen-printed carbon electrodes (SPCEs). The MIP layer was prepared by electrochemical in situ polymerization of the 3-amino-4 hydroxybenzoic acid (AHBA) functional monomer and CTL as a template molecule. To simulate the polymerization mixture and p...
Electropolymerized, Molecularly Imprinted Polymer on a Screen-Printed Electrode...
Seguro, Isabel; Rebelo, Patrícia; Pacheco, João; Delerue-Matos, CristinaIn recent years, analytical chemistry has been facing new challenges, particularly in developing low-cost, green, and easy-to-reproduce methods. In this work, a simple, reproducible, and low-cost electrochemical (voltammetric) molecularly imprinted polymer (MIP) sensor was designed specifically for the detection of trazodone (TZD). Trazodone (TZD) is an antidepressant drug consumed worldwide since the 1970s. By...