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IDN Jovem : 8º Seminário "IDN Jovem"

Ilin, Aleksandr; Pereira, Marta Lima; Matias, Leandro; Areias, Helena; Gonçalves, Mariana; Cardoso, Miguel; Silva, João; Suamo, Vasco; Falcone, Pedro

Date: 2024   |   Origin: Instituto da Defesa Nacional
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Biofilm matrix regulation by Candida glabrata Zap1 under acidic conditions: tra...

Gonçalves, Bruna Fernandes; Pires, Diana Priscila Penso; Fernandes, L.; Pacheco, Miguel; Ferreira, Tiago; Osório, Hugo; Soares, Ana Raquel

The vaginal acidic environment potentiates the formation of Candida glabrata biofilms, leading to complicated and recurrent infections. Importantly, the production of matrix is known to contribute to the recalcitrant features of Candida biofilms. In this study, we reveal that Zap1 regulates the matrix of C. glabrata acidic biofilms and analyzed the modulation of their transcriptome (by microarrays) and matrix p...

Date: 2024   |   Origin: RepositóriUM - Universidade do Minho
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