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Treatment patterns and preferences of people living with HIV starting or switch...

Pedro, L; Zagalo, A; Tavares, R; Pacheco, P; Oliveira, J; Vaz Pinto, I; Serrão, R; Tavares, S; Brito, P; Maltez, F; Neves, I; Carvalho, A; Teófilo, E

Background: There is a lack of up-to-date real-life evidence on antiretroviral therapy (ART) strategies among people living with HIV (PLWH) in Portugal. This study aimed to describe the treatment strategy used in PLWH either initiating or switching ART. Methods: Non-interventional, cross-sectional, multicenter study carried out between December 2019 and October 2021 in Portugal. Results: A total of 237 PLWH wer...

Date: 2024   |   Origin: Hospital de Cascais

Sociodemographic, Clinical, and Behavioral Factors Associated With Sexual Trans...

Miranda, M; Pimentel, V; Graça, J; Seabra, S; Sebastião, C; Diniz, A; Faria, D; Teófilo, E; Roxo, F; Maltez, F; Germano, I; Oliveira, J; Ferreira, J

Introduction: Sexually transmitted infections (STIs) continue to occur at high levels. According to the WHO, each year there are an estimated 374 million new infections with syphilis, gonorrhea, chlamydia, and trichomoniasis. STIs are associated with an increased risk of acquiring HIV infection. Migrants are reportedly highly affected by STIs. Objectives: This study aims to characterize factors associated with ...


HIV-1-Transmitted Drug Resistance and Transmission Clusters in Newly Diagnosed ...

Pingarilho, M; Pimentel, V; Miranda, M; Silva, AR; Diniz, A; Ascenção, B; Piñeiro, C; Koch, C; Rodrigues, C; Caldas, C; Morais, C; Faria, D

Objective: To describe and analyze transmitted drug resistance (TDR) between 2014 and 2019 in newly infected patients with HIV-1 in Portugal and to characterize its transmission networks. Methods: Clinical, socioepidemiological, and risk behavior data were collected from 820 newly diagnosed patients in Portugal between September 2014 and December 2019. The sequences obtained from drug resistance testing were us...


Surto 2019 nCoV

Jesus, R; Batista, J; Pacheco, P


Chronic Hepatitis C Treatment in HIV Co-Infection in Portugal: Results from a C...

Miranda, AC; Mendez, J; Serrão, R; Vale, F; Manata, MJ; Pinto, S; Gomes, A; Valente, C; Pacheco, P; Pazos, R; Pereira, R; Martins, A; Germano, I

Direct-acting antiviral drugs (DAAs) have recently changed the paradigm of hepatitis C therapy, significantly improving treatment response rates, patient life expectancy and quality of life. In Portugal, sofosbuvir (SOF) and SOF/ledipasvir (SOF/LDV) were fully reimbursed by the National Health System since early 2015 and generalized use of interferon-free DAA based regimens became current practice. During 2016,...


Artemether/Lumefantrine for the Treatment of P. malariae in a Patient on Hemodi...

Patrocínio-Jesus, R; Cunha, J; Trigo, D; Flor-de-Lima, B; Pacheco, P

The combination of artemether/lumefantrine is indicated for the treatment of acute uncomplicated Plasmodium falciparum malaria. There have been no clinical trials to assess the efficacy of this medication in patients with renal impairment. While it is unlikely that artemether/lumefantrine would be removed during dialysis, clinical experience regarding drug use in this setting is limited. In this article, the au...



Non-AIDS-Related Comorbidities in People Living with HIV-1 Aged 50 Years and Ol...

Serrão, R; Piñero, C; Velez, J; Coutinho, D; Maltez, F; Lino, S; Sarmento E Castro, R; Tavares, AP; Pacheco, P; Lopes, MJ; Mansinho, K; Miranda, AC

Objective: To characterize the profile of non-AIDS-related comorbidities (NARC) in the older HIV-1-infected population and to explore the factors associated with multiple NARC. Methods: This was a multicentre, cross-sectional study including HIV-1-infected patients aged ≥50 years, who were virologically suppressed and had been on a stable antiretroviral therapy (ART) regimen for at least 6 months. A multiple re...


Non-AIDS-related comorbidities in people living with HIV-1 aged 50 years and ol...

Serrão, R; Piñero, C; Velez, J; Coutinho, D; Maltez, F; Lino, S; Sarmento, E; Castro, R; Tavares, AP; Pacheco, P; Lopes, MJ; Mansinho, K; Miranda, AC

OBJECTIVE: To characterize the profile of non-AIDS-related comorbidities (NARC) in the older HIV-1-infected population and to explore the factors associated with multiple NARC. METHODS: This was a multicentre, cross-sectional study including HIV-1-infected patients aged ≥50 years, who were virologically suppressed and had been on a stable antiretroviral therapy (ART) regimen for at least 6 months. A multiple re...


Sarcoma de Kaposi oral

Gomes, F; Pires, J; Pacheco, P

O sarcoma de Kaposi é a neoplasia maligna mais frequente nos doentes seropositivos para o vírus da imunodeficiência humana, com envolvimento da cavidade orofaríngea num quarto dos doentes. Descreve-se o caso de uma doente com infeção pelo vírus da imunodeficiência humana, que se apresenta com uma massa vascularizada na base da língua, como primeira manifestação de sarcoma de Kaposi.


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