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Assessing response to stressful emotions: a controlled crossover study using pu...

Noronha, AC; Castro Mendes, F; Carvalho, P; Fonseca, M; Paciência, I; Moreira, A

"Background: Fear and horror induce autonomic protective responses, acting as ""survival intelligence."" Pupillometry is an innovative method that captures real-time autonomic nervous system reactions to stress. Objective: To evaluate the feasibility of pupillometry to assess the acute response to a passive real-life stressor-viewing a truthful war scene. Methods: Thirteen medical students (10 women) with an av...


Diet quality, asthma and airway inflammation in school-aged children

Rodrigues, M; de Castro Mendes, F; Paciência, I; Barros, Renata; Padrão, Patrícia; Cavaleiro Rufo, J; Cavaleiro, D; Delgado, L; Moreira, A


Mediterranean Diet and Airway Inflammation in School-Aged Children

Rodrigues, M; de Castro Mendes, F; Padrão, Patrícia; Delgado, L; Paciência, I; Barros, Renata; Rufo, JC; Silva, D; Moreira, André; Moreira, Pedro

<jats:p>There seems to exist an intricate relationship between airway inflammation, body mass index (BMI), and diet. The intake of specific foods or food groups has been suggested to suppress the oxidative stress and inflammatory processes that characterize airway inflammation, but little is known about dietary patterns and their complex interplay with BMI and airway inflammation. Therefore, this cross-sectiona...


Cost-effectiveness analysis of grass pollen specific immunotherapy in children ...

Farraia, M; Paciência, I; Mendes, FC; Cavaleiro Rufo, J; Delgado, L; Moreira, A

Background. Cost-effectiveness studies evaluating allergen immunothera-py (AIT) in children are scarce. We aim to compare the cost-effectiveness of subcutaneous (SCIT) and sublingual immunotherapy (SLIT) against stan-dard-of-care (SOC) treatment in children with grass pollen allergic rhinitis. Methods. We created a Markov model to compare the three strategies over a 10-year horizon. SOC was the reference to cal...


Childhood asthma and land-use characteristics in school and residential neighbo...

Paciência, I; Cavaleiro Rufo, J; Ribeiro, AI; Severo, M; Moreira, A


Environmental inequality: Air pollution and asthma in children

Paciência, I; Cavaleiro Rufo, J; Moreira, A

Introduction: Whether you benefit from high-quality urban environments, such as those rich in green and blue spaces, that may offer benefits to allergic and respiratory health depends on where you live and work. Environmental inequality, therefore, results from the unequal distribution of the risks and benefits that stem from interactions with our environment. Methods: Within this perspective, this article revi...


Allergen immunotherapy for asthma prevention: A systematic review and meta-anal...

Farraia, M; Paciência, I; Castro Mendes, F; Cavaleiro Rufo, J; Shamji, M; Agache, I; Moreira, A

Background: Allergen immunotherapy (AIT) is a disease-modifying treatment for IgE-mediated diseases. Randomized controlled trials (RCTs) support AIT's potential role in asthma prevention but evidence from non-randomized studies of interventions (NRSI) and longitudinal observational studies has been poorly addressed. Therefore, we aimed to conduct a systematic review and meta-analysis to assess clinical data fro...


Green and blue spaces and lung function in the Generation XXI cohort: a life-co...

Almeida, DQ; Paciência, I; Moreira, C; Rufo, JC; Moreira, A; Santos, AC; Barros, H; Ribeiro, AI

Background Exposure to natural environments may affect respiratory health. This study examined the association of exposure to green and blue spaces with lung function in children, and assessed the mediation effect of air pollution and physical activity. Methods The study used data from the Generation XXI, a population-based birth cohort from the Porto Metropolitan Area (Portugal). Residential Normalised Differe...


AlergiaPT: A Portuguese media campaign to inspire people with allergies to make...

Moreira, A.; Mendes, F.C.; Rama, T.; Mota, D.; Silva, D; Pádua, I.; Abreu, C; Vasconcelos, MJ; Farraia, M; Paciência, I; Rufo, J; Barros, Renata


Neighbourhood Socioeconomic Processes and Dynamics and Healthy Ageing: A Scopin...

Santos, CJ; Paciência, I; Ribeiro, AI

Elderly citizens are concentrated in urban areas and are particularly affected by the immedi-ate residential environment. Cities are unequal and segregated places, where there is an intensification of urban change processes such as gentrification and displacement. We aimed to understand how neighbourhood socioeconomic processes and dynamics influence older people’s health. Three biblio-graphic databases—PubMed,...


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