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Diet Quality and Exhaled Breath Condensate Markers in a Sample of School-Aged C...

Rodrigues, M; Mendes, FD; Paciencia, I; Rufo, JC; Silva, D; Delgado, L; Moreira, André; Moreira, Pedro

Exhaled breath condensate (EBC) analysis is a recently developed, non-invasive method used to identify and quantify biomarkers, mainly those coming from the lower respiratory tract. It seems that diet can influence the airway's inflammation and change the exhaled breath composition. This study aimed to assess the association between diet quality intake and markers in EBC among school-aged children. A cross-sect...


Dietary Acid Load Modulation of Asthma-Related miRNAs in the Exhaled Breath Con...

Mendes, FC; Paciencia, I; Rufo, JC; Silva, D; Delgado, L; Moreira, André; Moreira, Pedro

Individual nutrients and bioactive compounds have been implicated in the expression of microRNAs (miRNAs), which are related to inflammation and asthma. However, evidence about the impact of diet is scarce. Therefore, we aimed to assess the association between dietary acid load and asthma-related miRNA in the exhaled breath condensate (EBC) of school-aged children. This cross-sectional analysis included 150 par...


Increasing Vegetable Diversity Consumption Impacts the Sympathetic Nervous Syst...

Mendes, FD; Paciencia, I; Rufo, JC; Farraia, M; Silva, D; Padrão, Patrícia; Delgado, L; Garcia Larsen, V; Moreira, André; Moreira, Pedro

Evidence about the impact of vegetable and fruit diversity consumption on the autonomic nervous system (ANS) functioning is scarce. In this cross-sectional study (513 participants, 49.9% girls aged 7 to 12 years), we evaluated the association between vegetable and fruit diversity consumption and the ANS in school-aged children. Dietary intake was collected using a single 24-h recall questionnaire. Fruit and veg...


Bronchodilator responsiveness in healthy children: Insights from a cross-sectio...

Tiago Rama; Martins, C; Paciencia, I; Rufo, J; Silva, D; Mendes, FC; Severo, M; Padrão, Patrícia; Moreira, Pedro; Delgado, L; Moreira, A


Exhaled breath condensate pH determinants in school-aged children: A population...

Tiago Rama; Paciencia, I; Rufo, JC; Silva, D; Cunha, P; Severo, M; Padrão, Patrícia; Moreira, Pedro; Delgado, L; Moreira, André

Background Exhaled breath condensate (EBC) pH is a promising biomarker of airway inflammation. Lack of method standardization and interstudy variability precludes its use in clinical practice. While endogenous determinants have been described, underlying mechanisms for variability are mostly unknown. Thus, we aimed to assess the association between asthma and EBC pH in children, while studying potential environ...


Higher diversity of vegetable consumption is associated with less airway inflam...

Mendes, FD; Paciencia, I; Rufo, JC; Farraia, M; Silva, D; Padrão, Patrícia; Delgado, L; Garcia Larsen, V; Moreira, A; Moreira, Pedro

Background A diet rich in fruits and vegetables has been suggested to counteract the oxidative stress and inflammation that characterize asthma. We aimed to assess the association between vegetable and fruit diversity consumption and asthma and its related outcomes in school-aged children. Methods Participants included 647 children (49% females, aged 7-12 years) recruited from 20 public schools across the city ...


The Influence of Eating at Home on Dietary Diversity and Airway Inflammation in...

de Castro Mendes, F; Cunha, P; Paciencia, I; Rufo, JC; Farraia, M; Silva, D; Padrão, Patrícia; Delgado, L; Moreira, André; Moreira, Pedro

Considering the negative impact of a lack of dietary diversity on children's nutritional status, we aimed to describe dietary variety according to eating at home frequency and assessed its association with respiratory outcomes in school-aged children. This cross-sectional study included 590 children (49% girls) aged 7 to 12 years from 20 public schools located in city of Porto, Portugal. Daily frequency of eati...


Effects of Exercise on the Skin Epithelial Barrier of Young Elite Athletes-Swim...

Paciencia, I; Rodolfo, A; Leao, L; Silva, D; Rufo, JC; Mendes, F; Padrão, Patrícia; Moreira, Pedro; Boechat, JL; Delgado, L; Moreira, André

The benefits of swimming have been extensively assessed. However, swimming pools contain chlorine and other irritating chemicals that may induce contact dermatitis. To evaluate the effect of a swimming training session on transepidermal water loss (TWEL) in swimmers compared to football players, elite swimmers and football players were invited to participate (58 athletes) in the study, where TEWL was measured b...


School environment associates with lung function and autonomic nervous system a...

Paciencia, I; Rufo, JC; Silva, D; Martins, C; Mendes, F; Rama, T; Rodolfo, A; Madureira, J; Delgado, L; Fernandes, ED; Padrão, Patrícia; Moreira, Pedro

Children are in contact with local environments, which may affect respiratory symptoms and allergic sensitization. We aimed to assess the effect of the environment and the walkability surrounding schools on lung function, airway inflammation and autonomic nervous system activity. Data on 701 children from 20 primary schools were analysed. Lung function, airway inflammation and pH from exhaled breath condensate ...


Swimming pool exposure is associated with autonomic changes and increased airwa...

Rufo, JC; Paciencia, I; Silva, D; Martins, C; Madureira, J; Fernandes, ED; Padrão, Patrícia; Moreira, Pedro; Delgado, L; Moreira, André

Background Endurance swimming exercises coupled to disinfection by-products exposure has been associated with increased airways dysfunction and neurogenic inflammation in elite swimmers. However, the impact of swimming pool exposure at a recreational level on autonomic activity has never been explored. Therefore, this study aimed to investigate how swimming pool attendance is influencing lung and autonomic func...


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