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Preserving accuracy in GenBank

Bidartondo, M. I.; Bruns, T. D.; Blackwell, M.; Edwards, I.; Taylor, A. F. S.; Horton, T.; Zhang, N.; Koljalg, U.; May, G.; Kuyper, T. W.; Gilbert, G.

GenBank, the public repository for nucleotide and protein sequences, is a critical resource for molecular biology, evolutionary biology, and ecology. While some attention has been drawn to sequence errors (1), common annotation errors also reduce the value of this database. In fact, for organisms such as fungi, which are notoriously difficult to identify, up to 20% of DNA sequence records may have erroneous lin...


Assembling the fungal tree of life: progress, classification, and evolution of ...

Lutzoni, F.; Kauff, F.; Cox, C. J.; McLaughlin, D.; Celio, G.; Dentinger, C.; Padamsee, M.; Hibbett, D. S.; James, T. Y.; Baloch, E.; Grube, M.

Based on an overview of progress in molecular systematics of the true fungi(Fungi/Eumycota) since 1990, little overlap was found among single-locus data matrices, which explains why no large-scale multilocus phylogenetic analysis had been undertaken to reveal deep relationships among fungi. As part of the project ‘‘Assembling the Fungal Tree of Life’’ (AFTOL), results of four Bayesian analyses are reported with...


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