13 documents found, page 1 of 2
Azadirachta indica A. Juss (neem) phenolic extract inhibits human B-lymphoblast...
Santos, Klebson Silva; Costa, Carla; Bessa, Maria João; Teixeira, João Paulo; Muniz, Ana Veruska Cruz da Silva; Padilha, Francine FerreiraAim: As far as is known, the pharmaceutical effects of neem on human B-lymphoblastoid (TK6) cells have not been studied until now. Hence, the present study aimed to obtain neem phenolic extracts for inhibits the proliferation of TK6 cells and explore some possible underlying mechanisms involved in these effects. Methods: Hexane extract (HE) was obtained in the first step. After that, the residual hexane was rem...
Optimization of xanthan gum production by demerara sugar using response surface...
Ramos, Larissa Castor; Jesus, Meirielly Santos; Pires, Preciosa; Fontes-Junior, Alberto S.; Nunes, Erica S.; Santos, Klebson S.; Teixeira, J. A.Xanthan gum (XG) production using three Xanthomonas sp. strains (290, 472, and S6) was evaluated by applying a 23 full factorial central composite design response to study the interactive effects of the fermentation medium component concentrations as parameters to determine the efficiency of the gum production in batch experiments. The experimental variables were the carbon source (demerara sugar or sucrose), p...
Scientific and technological prospection of Tabebuia reseoalba (Ipê-branco)
Pereyra, Beatriz Benny Sungaila; Santos, Tatiane Batista dos; Rocha, Felipe Santos; Costa, Bárbara de Jesus; Costa, Any Gabrielly de JesusTabebuia roseoalba, popularly known as Ipê-branco, a plant native to the Brazilian cerrado and wetlands. As it has numerous substances of therapeutic interest, there are perspectives of serving as an alternative in the control of infections. In order to verify the importance of the extracts of Tabebuia roseoalba in the scientific nature, researches were carried out in order to confirm the relevance that the pre...
Scientific and technological prospection study on Myracrodruon urundeuva (aroei...
Sousa, Davi Santana; Rodrigues, Giancarlos Costa; Gaspar, Lívia Maria do Amorim Costa; Machado, Tatiane de Oliveira Xavier; Valverde, Fernanda GuimarãesMultiresistant bacteria have been one of the main causes of infection and nosocomial permanence. This is attributed to its ability to acquire resistance to several antibiotics, both through the incorrect use of these drugs and the accommodation to the proposed treatment. Thus, for these bacteria, conventional treatment with antibiotics does not have the potential to eliminate them, so different strategies have ...
Scientific and technological prospection of potential immunotherapies including...
Santos, Tatiane Batista dos; Gomes, Denilson dos Santos; Sousa , Alícia Beatriz Fontes de; Rodrigues, Ítalo Samuel Gonçalves; Padilha, Francine FerreiraOsteosarcoma (OS) is a malignant bone tumor whose treatment is performed through surgical removal associated with combined chemotherapy, which include the use of medications. In order to verify the importance of immunotherapy in a scientific way, researches were carried out in order to confirm the relevance that the study presents as a technological innovation. For this, the PubMed and Science Direct article li...
Otoliths-composed gelatin/sodium alginate scaffolds for bone regeneration
Valido, Daisy Pereira; Júnior, Wilson Déda Gonçalves; de Andrade, Maria Eliane; Rezende, Allan Andrade; de Andrade de Carvalho, Felipe MendesEvidence that otoliths, mineral-rich limestone concrescences present in the inner ear of bone fishes, can accelerate bone formation in vivo has been previously reported. The goal of this work was the development, characterization, and evaluation of the cytocompatibility of otoliths-incorporated sodium alginate and gelatin scaffolds. Cynoscion acoupaderived otoliths were characterized by X-ray fluorescence spect...
Brazilian red propolis: extracts production, physicochemical characterization, ...
de Carvalho, Felipe Mendes de Andrade; Schneider, Jaderson Kleveston; de Jesus, Carla Viviane Freitas; de Andrade, Luciana NaloneBrazilian red propolis has been proposed as a new source of compounds with cytotoxic activity. Red propolis is a resinous material of vegetal origin, synthesized from the bees of the Appis mellifera family, with recognized biological properties. To obtain actives of low polarity and high cytotoxic profile from red propolis, in this work, we proposed a new solvent accelerated extraction method. A complete 23 fac...
Induction and growth curve of calli from leaf and nodal explants of genipap
de Oliveira, Annie Carolina Araújo; Machado, Caroline de Araújo; Resende de Oliveira, Leila Albuquerque; Padilha, Francine FerreiraThe aim of this study was to determine the effect of the auxin 2,4-D (2,4-dichlorophenoxyacetic) in calli formation from leaf and nodal segments of genipap and to characterize its growth curve. Explants obtained from shoots previously established from in vitro seedlings were used for calli induction. The experimental design was completely randomized in a 3x5x2 factorial with three accessions (NB, SA, SAL), five...
Effect of green propolis on oral epithelial dysplasia in rats
Soares, Andrea Ferreira; Cavalcante, Danielle Rodrigues Ribeiro; Oliveira, Paula Santos de; Góis, Sandro Mota; Soares, Andrea FerreiraStudies have demonstrated that flavonoid compounds of green propolis have antitumoral activity. Study Design: Experimental study. Aims: To evaluate the effect of a hydroalcoholic extract of green propolis (EPV) on chemically induced epithelial dysplasias in rat tongues. Methods and Materials: DMBA was brushed on the lingual dorsum of rats 3x/week on alternate days - 100 (PROP1), 200 (PROP2) and 300 mg/kg (PROP3...
In vitro biological potential of Guanxuma-of-Horn [Sebastiania corniculata (Vah...
Silva, Isabelle Souza de Mélo; Santos, Raíssa Fernanda Evangelista Pires dos; Melo, Thiane de Vasconcellos Costa; Silva, Ana Jéssica Cassimiro daMedicinal plants with antimicrobial properties built into the problem of infection have been investigated, guide the discovery of efficient against the emerging pathogens herbal related to bacterial and fungal infection. This study aimed to enlarge the possibilities of knowledge about antibacterial and antifungal activities of this plant, in the treatment of infections. The results of antimicrobial activity and...