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Plasma-treated bacterial nanocellulose-lignin composites for biomedical applica...

Alves, Cátia; Melro, Liliana Sofia Silva Ferreira Pinto; Fernandes, Marta; Padrão, Jorge; Moldes, Diego; Serra, Sofia Cravino; Salgado, A. J.

Bacterial nanocellulose (BC) as a bioimplant possesses several limitations, encompassing absence of bioactivity, and unsatisfactory mechanical properties. Envisaging antimicrobial activity, enhanced cytocompatibility and mitigation of the inflammatory response, surface characteristics such as hydrophilicity and rugosity were tailored. Different strategies comprising treatments with Kraft lignin (KL), glycerin (...


Antibacterial and antioxidant performance of natural textile dyes for children’...

Santiago, Diana Filipa Fonseca; Mehravani, Behnaz; Alves, Cátia Sofia Pereira; Cabral, Isabel; Cunha, Joana; Zille, Andrea; Padrão, Jorge

Children’s skin is highly sensitive and prone to irritation, allergies, and infections, requiring special consideration in textile selection. Although clothing serves as a protective barrier, it can also pose a risk when dyed with toxic chemical colourants. This study explores the potential of multifunctional natural dyes as safer alternatives for children’s clothing, particularly for those with dermatological ...


Sustainable shear wave elastography medical phantoms: waste-based fibrous struc...

Santos, Ana Isabel Zão; Rocha, Sofia Gomes; Fernandes, Nuno Alexandre Tavares Campos; Alves, Diana Isabel Sousa; Ferreira, Diana P.

Tissue-mimicking phantoms that accurately replicate human tissue are crucial for validating and optimizing elastography systems and developing new treatment methods. The use of waste-based fibrous structures has the dual benefits of waste reduction and economic viability, mitigating the environmental consequences associated with the textile industry and, thus, posing a particularly interesting avenue of researc...


Elastic bands antimicrobial functionalization

Ferreira, Ana Francisca; Fernandes, Rui Daniel Vilaça; Vieira, Bárbara Marques; Peixoto, Joaquim Jorge Gomes; Felgueiras, Helena Prado; Zille, Andrea

Sustainability of textile products encompasses the extension of their useful life period during which they adequately serve their intended purpose. Antimicrobial finishings can prevent microbial damage and extend textile lifespan. Even though the functionalization and characterization processes have been thoroughly described for woven, knitted and non-woven textiles, there is a lack of information regarding ela...


DBD plasma-treated polyester fabric coated with doped PEDOT:PSS for thermoregul...

Magalhães, Cátia; Ribeiro, Ana Isabel Ferreira; Rodrigues, Rui; Meireles, Ângela; Alves, Alexandra C.; Rocha, João Pedro Costa; Pedroso de Lima, Fábio

The manufacturing process of thermoregulation products with polyester (PES) fabric and conductive polymers such as poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulfonate) (PEDOT:PSS) with proper wearability, comfort, and high performance is still a challenge due to low adhesion, environment instability and nonuniform coatings. This study presents a simple and effective method for producing thermoreg...


Bacterial nanocellulose as a versatile scaffold for biomedical applications: sy...

Melro, Liliana Sofia Silva Ferreira Pinto; Alves, Cátia Sofia Pereira; Fernandes, Marta Susana Machado; Rocha, Sofia Gomes; Mehravani, Behnaz

Bacterial nanocellulose (BNC) consists of nanofibres of cellulose randomly entangled during their synthesis by particular bacterium cells during fermentation. Thus, it may be regarded as a unique three-dimensional of pure cellulose that is consolidated during the generation of the fibres by their microbiological factories. The metabolic synthesis and purification processes are approached, underscoring its poten...


Plasma-treated bacterial nanocellulose-lignin composites for neuralgia implants

Alves, Cátia Sofia Pereira; Melro, Liliana Sofia Silva Ferreira Pinto; Fernandes, Marta Susana Machado; Padrão, Jorge; Moldes, Diego

[Excerpt] This research envisages the use of bacterial nanocellulose (BNC) as a biomaterial for implants to mitigate neuralgias, focusing on the material's inherent limitations. BNC is widely valued for its excellent mechanical properties, ease of modification, and non-anthropogenic degradability [1]. However, its absent electrical conductivity, insufficient antimicrobial activity, and weak interaction with neu...


Active wound dressing of electrospun lignin/cellulose acetate on cotton gauze

Mehravani, Behnaz; Fernandes, Marta Susana Machado; Alves, Cátia Sofia Pereira; Melro, Liliana Sofia Silva Ferreira Pinto; Fernandes, Rui Daniel Vilaça

Wounds that do not heal within a reasonable time frame can be considered as chronic wounds and it is estimated that 1.51 to 2.21 per 1000 people worldwide are suffering from this condition [1]. Chronic wounds can be characterized as permanently in the inflammatory stage. This stage comprises a continuing influx of neutrophils that release cytotoxic enzymes, reactive oxygen species (ROS), and inflammatory mediat...


Cellulosic fabrics bio-finishing with natural products

Fernandes, Rui Daniel Vilaça; Magalhães, Renata Sofia Vieira; Rodrigues, Soraia Cristina Vieira; Vieira, Bárbara Marques; Alves, Cátia Sofia Pereira

[Excerpt] Results: Propolis (a byproduct of beehives), Kraft lignin (extracted from trees or plants), and olive pomace (a byproduct of olive oil production) were used to confer antimicrobial properties to cotton (CO), linen (CL), and hemp (CH) fabrics. Fabrics functionalized with propolis can be classified as weak disinfectants, and olive pomace fabrics are considered strong decontaminants, both against Staphyl...


In vitro optimization of photobiomodulation and ultrasound stimulation protocol...

Monteiro, Francisca; Oliveira, Sofia; Marques, Carlos; Papadimitriou, Georgia; Silva, Joana M.; Padrão, Jorge; Sotiropoulos, Ioannis; Catarino, Susana

The effectiveness of transcranial photobiomodulation (tPBM) and ultrasound stimulation (tUS) to mitigate different neuropathological mechanisms and stimulate neuroprotective responses has been vastly demonstrated in preclinical disease models. However, the translation into clinics is still suboptimal, revealing the need for more solid basic research to ascertain the most effective stimulation parameters to modu...


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