Made available in DSpace on 2018-12-11T17:06:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The production of ergosterol lipid, important for the Leishmania membrane homeostasis, involves different enzymes. This pathway can be blocked to azoles and allylamines drugs, such as Butenafine. The aim of the present work was to evaluate t...
Made available in DSpace on 2018-12-11T17:08:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-04-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Leishmaniasis is an important neglected tropical disease, affecting more than 12 million people worldwide. The available treatments are not well tolerated and present diverse side effects in patients, justifying the search for new therapeuti...