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p-Methoxycinnamic acid diesters lower dyslipidemia, liver oxidative stress and ...

Paim, Raquel Teixeira Terceiro; Rodrigues, Paula Salmito Alves; Silva, José Ytalo Gomes da; Paula Junior, Valdir Ferreira de; Silva, Bruno Bezerra da

The pursuit of cholesterol lowering natural products with less side e ects is needed for controlling dyslipidemia and reducing the increasing toll of cardiovascular diseases that are associated with morbidity and mortality worldwide. The present study aimed at the examining e ects of p-methoxycinnamic acid diesters (PCO-C) from carnauba (Copernicia prunifera)-derived wax on cytotoxic, genotoxic responses in vit...

Date: 2020   |   Origin: Oasisbr

Hypolipidemic activity of P-methoxycinnamic diester (PCO-C) isolated from Coper...

Arruda Filho, Antônio Casella V.; Rodrigues, P. A. S.; Benjamin, Stephen Rathinaraj; Paim, Raquel Teixeira Terceiro; Holanda, M. O.; Silva, J. Y. G.

Carnauba wax is extracted from the leaves of the Copernicia prunífera and contains approximately 80% of esters in its composition. The purpose of the present study was evaluate the hypolipidemic effect of p-methoxycinnamic diesters (PCO-C) extracted from Copernicia prunífera in a model of acute and chronic dyslipidemia in mice. The levels of total cholesterol and triglycerides were significantly reduced plasma ...

Date: 2018   |   Origin: Oasisbr

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