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Evaluation of a selective chromogenic medium for detecting vancomycin-resistant...
Soares,Renata Oliveira; Rossato,Adriana Medianeira; Sambrano,Gustavo Enck; Tolfo,Neidimar Cezar Corrêa; Caierão,Juliana; Paim,Thiago Galvão da SilvaABSTRACT Rapid identification of vancomycin-resistant enterococci (VRE) can assist in choosing the appropriate treatment and preventing VRE spread. The performance of chromIDTM VRE agar was evaluated using 184 clinical isolates of Enterococcus spp. and reference strains. The test had a sensitivity of 95.52% but a low specificity of 30%.
Rifampicin fails to eradicate mature biofilm formed by methicillin-resistant St...
Reiter,Keli Cristine; Sambrano,Gustavo Enck; Villa,Bárbara; Paim,Thiago Galvão da Silva; Oliveira,Caio Fernando de; d'Azevedo,Pedro AlvesINTRODUCTION: Antimicrobial activity on biofilms depends on their molecular size, positive charges, permeability coefficient, and bactericidal activity. Vancomycin is the primary choice for methicillin-resistant Staphylococcus aureus (MRSA) infection treatment; rifampicin has interesting antibiofilm properties, but its effectivity remains poorly defined. METHODS: Rifampicin activity alone and in combination wit...