9 documents found, page 1 of 1

Identification of novel metabolic signatures on human gut microbiota: ellagic a...

Phenolic compounds are widely known for their beneficial effects on human health. However, it is essential to understand which low molecular weight metabolites are produced by the gut microbiota, when non-absorbed compounds reach the colon, and whether these metabolites are more biologically active than their precursors. In this context, this study aims to explore the gut microbiota metabolites of relevant phen...

Phenolic compounds as modulators of gut microbiota composition: an in vitro bat...

The human diet comprises a variety of bioactive compounds, such as phenolic compounds which are widely present in vegetables and fruits that confer numerous health benefits.1 However, the health benefits of these compounds appear to be directly influenced by a number of factors, including their bidirectional relationship with gut microbiota,1,2 as these compounds are metabolized by these microorganisms, and, si...

Exploring the bioaccessibility and intestinal absorption of major classes of pu...

The bioaccessibility and bioavailability of phenolic compounds (PC) influence directly their role in disease prevention/control. Studies have evaluated this ability through complex plant and food matrices, which may reflect more a synergistic effect of the matrix than the ability of the PCs, hindering their individual exploitation in nutraceutical or pharmaceutical applications. In the present study ten pure PC...

Gut microbiota modulation induced by pure phenolic compounds: an in vitro fecal...

Exploring the bioavailability of phenolic compounds through in vitro simulated ...

Conclusions: Studied phenolic compounds did not undergo enzymatic digestion after INFOGEST, as we did not detect any resultant metabolites. Bioaccessibility percentages determined after the intestinal digestion phase showed that most of the studied phenolic compounds were about 50% bioaccessible. Absorption rates of all studied phenolic compounds were high (> 80%), suggesting that they can be absorbed into the ...

Metabolism of phenolic compounds by human gut microbiota: insights from in vitr...

Screening of different phenolic compounds classes bioavailability and bioaccess...

Introduction: For centuries, plants have been seen by humans as an essential source of food or natural healthcare products.1 In an effort to improve consumers health' and well-being, much effort is being centered on the exploitation of their biological activities.2 Phenolic compounds are secondary metabolites with a huge structural diversity and widely distributed in the plant kingdom, and thus, commonly presen...

Polar lipids of commercial Ulva spp. of different origins: profiling and releva...

Macroalgae of the genus Ulva have long been used as human food. Local environmental conditions, among other factors, can have an impact on their nutrient and phytochemical composition, as well as on the value of the seaweed for food and non-food applications. This study is the first to initiate a comparison between commercial Ulva spp. from different European origins, France (FR, wild-harvested Ulva spp.), and ...

The Quest for Phenolic Compounds from Macroalgae: A Review of Extraction and Id...

The current interest of the scientific community for the exploitation of high-value compounds from macroalgae is related to the increasing knowledge of their biological activities and health benefits. Macroalgae phenolic compounds, particularly phlorotannins, have gained particular attention due to their specific bioactivities, including antioxidant, antiproliferative, or antidiabetic. Notwithstanding, the char...