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Cutaneous infection with the cytomegalovirus virus in AIDS patients.

Franca, I; Poiares-Baptista, A; Pais, M J; Araújo, C; Chorão, M; Ricardo, J L; Mansinho, K

Cutaneous cytomegalovirus (CMV) infection has been observed in a variety of nonspecific skin lesions. Because of this fact, its diagnosis is rare and frequently accidental. The presence of the virus has also been observed in apparently normal skin, from both a clinical and histological point of view. In this context, skin biopsy and immunohistochemistry are often the first means of diagnosis of systemic CMV inf...

Date: 1997   |   Origin: Acta Médica Portuguesa

Cyclosporin A--a therapeutic alternative in giant-cell arteritis?.

Sampaio, J; Pais, M J; Lebre, L; Sousa, A; Martins, A P; Simões, J

Cyclosporine A (CyA) is an immune modulator that may treat immune diseases. The authors present two cases of temporal arteritis treated with CyA; the two patients improved very quickly and after the first six or eight weeks of treatment there were no clinical or laboratory signs of inflammation. As to adverse effects there was a moderate increase in serum creatinine and arterial pressure levels which were contr...

Date: 1993   |   Origin: Acta Médica Portuguesa

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