34 documents found, page 1 of 4

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Results of Surgery Versus Stereotactic Body Radiotherapy for Lung Cancer

Costa, R; Aires, F; Rodrigues, D; Paiva, A; Maciel, J; Fernandes, P


Strategy Nursing in Children with Compromised Ventilation: Umbrella Review

Reis, N; Gaspar, LJ; Paiva, A; Pereira, F; Sousa, P; Machado, N

Problem: Changes in the ventilation demand nursing interventions duly adapted to the management of said impairment and to the adaptability of the child/parents. This revision aimed to investigate the evidence behind the interventions performed on children with impaired ventilation.' Eligibility criteria: Systematic reviews of literature in English, Spanish, French, and Portuguese from studies on nursing interve...


Endometrial Cancer Spheres Show Cancer Stem Cells Phenotype and Preference for ...

Carvalho, MJ; Laranjo, M; Abrantes, AM; Casalta-Lopes, J; Sarmento-Santos, D; Costa, T; Serambeque, B; Almeida, N; Gonçalves, T; Mamede, C

This study aimed to characterize endometrial cancer regarding cancer stem cells (CSC) markers, regulatory and differentiation pathways, tumorigenicity and glucose metabolism. Endometrial cancer cell line ECC1 was submitted to sphere forming protocols. The first spheres generation (ES1) was cultured in adherent conditions (G1). This procedure was repeated and was obtained generations of spheres (ES1, ES2 and ES3...


Lifelong training improves anti-inflammatory environment and maintains the numb...

Minuzzi, LG; Rama, L; Bishop, NC; Rosado, F; Martinho, A; Paiva, A; Teixeira, AM

PURPOSE: The purpose of this study was to quantify and characterize peripheral blood regulatory T cells (Tregs), as well as the IL-10 plasma concentration, in Masters athletes at rest and after an acute exhaustive exercise test. METHODS: Eighteen Masters athletes (self-reported training: 24.6 ± 1.83 years; 10.27 ± 0.24 months and 5.45 ± 0.42 h/week per each month trained) and an age-matched control group of ten...


Oxidative Stress, DNA, Cell Cycle/Cell Cycle Associated Proteins and Multidrug ...

Mamede, Ana Catarina Manjolinha; Guerra, S; Laranjo, Marta; Santos, K; Carvalho, Maria J; Carvalheiro, Tiago; Moura, P; Paiva, A; Abrantes, Ana M

The anticancer effects of human amniotic membrane (hAM) have been studied over the last decade. However, the action mechanisms responsible for these effects are not fully understood until now. Previously results reported by our team proved that hAM is able to induce cytotoxicity and cell death in hepatocellular carcinoma (HCC), a worldwide high incident and mortal cancer. Therefore, this experimental study aime...

Date: 2016   |   Origin: uBibliorum

Harmonemia: a universal strategy for flow cytometry immunophenotyping-A Europea...

Lacombe, F; Bernal, E; Bloxham, D; Couzens, S; Porta, M G D; Johansson, U; Kern, W; Macey, M; Matthes, T; Morilla, R; Paiva, A; Palacio, C; Preijers, F


Accelerated age-related olfactory decline among type 1 Usher patients

Ribeiro, JC; Oliveiros, B; Pereira, P; António, N; Hummel, T; Paiva, A; Silva, E

Usher Syndrome (USH) is a rare disease with hearing loss, retinitis pigmentosa and, sometimes, vestibular dysfunction. A phenotype heterogeneity is reported. Recent evidence indicates that USH is likely to belong to an emerging class of sensory ciliopathies. Olfaction has recently been implicated in ciliopathies, but the scarce literature about olfaction in USH show conflicting results. We aim to evaluate olfac...


Aberrant p15, p16, p53, and DAPK Gene Methylation in Myelomagenesis: Clinical a...

Geraldes, C; Gonçalves, AC; Cortesão, E; Pereira, MI; Roque, A; Paiva, A; Ribeiro, L; Nascimento-Costa, JM; Sarmento-Ribeiro, AB

BACKGROUND: Aberrant DNA methylation is considered a crucial mechanism in the pathogenesis of monoclonal gammopathies. We aimed to investigate the contribution of hypermethylation of 4 tumor suppressor genes to the multistep process of myelomagenesis. METHODS: The methylation status of p15, p16, p53, and DAPK genes was evaluated in bone marrow samples from 94 patients at diagnosis: monoclonal gammopathy of unce...


Oxidative Stress, DNA, Cell Cycle/Cell Cycle Associated Proteins and Multidrug ...

Mamede, AC; Guerra, S; Laranjo, M; Santos, K; Carvalho, MJ; Carvalheiro, T; Moura, P; Paiva, A; Abrantes, AM; Maia, CJ; Botelho, MF

The anticancer effects of human amniotic membrane (hAM) have been studied over the last decade. However, the action mechanisms responsible for these effects are not fully understood until now. Previously results reported by our team proved that hAM is able to induce cytotoxicity and cell death in hepatocellular carcinoma (HCC), a worldwide high incident and mortal cancer. Therefore, this experimental study aime...



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