16 documents found, page 1 of 2
Functional Outcome of Endovascular Treatment in Patients With Acute Ischemic St...
Ferreira Cristina, S; Fior, A; Alves, M; Papoila, AL; Paiva Nunes, AIntroduction Endovascular treatment (EVT) with mechanical thrombectomy and acute carotid stenting has become an integral part of the treatment of acute ischemic stroke with large vessel occlusion. Despite being included in the most recent stroke guidelines, only comprehensive centers can offer EVT and thus patients frequently need to be transferred from primary hospitals. We aimed to assess which pre-hospital m...
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
Carvalho Dias, M; Soares dos Reis, R; Santos, JV; Paiva Nunes, A; Ferreira, P; Maia, B; Fragata, I; Reis, J; Ramos Lopes, J; Cruz, L; Santo, GIntroduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular ...
Endovascular Treatment of Pediatric Ischemic Stroke: a Single Center Experience...
Fragata, I; Morais, T; Silva, R; Paiva Nunes, A; Loureiro, P; Martins, JD; Pamplona, J; Carvalho, R; Baptista, M; Reis, JIntroduction: Mechanical thrombectomy is standard treatment for large vessel occlusion (LVO) in adults. There are no randomized controlled trials for the pediatric population. We report our single-center experience with thrombectomy of LVO in a series of pediatric patients, and perform a review of the literature. Methods: Retrospective review of consecutive pediatric thrombectomy cases between 2011 and 2018. De...
Functional Outcome after Mechanical Thrombectomy with or without Previous Throm...
Machado, M; Alves, M; Fior, A; Fragata, I; Papoila, AL; Reis, J; Paiva Nunes, AIntroduction: Combined intravenous therapy (IVT) and mechanical thrombectomy (MT) is the standard treatment for acute ischemic stroke (AIS) with large vessel occlusion (LVO). However, the use of IVT before MT is recently being questioned. Objectives: To compare patients treated with IVT before MT with those treated with MT alone, in a real-world scenario. Methods: Retrospective analysis of AIS patients with LVO...
Safety and Outcomes of Routine Endovascular Thrombectomy in Large Artery Occlus...
Ahmed, N.; Mazya, M.; Paiva Nunes, A; Moreira, T; Ollikainen, JP; Escudero‐Martinez, I; Bigliardi, G; Dorado, L; Dávalos, A; Egido, JA; Tassi, RBackground and objective: We aimed to evaluate the safety and outcomes of thrombectomy in anterior circulation acute ischaemic stroke recorded in the SITS-International Stroke Thrombectomy Register (SITS-ISTR) and compare them with pooled randomized controlled trials (RCTs) and two national registry studies. Methods: We identified centres recording ≥10 consecutive patients in the SITS-ISTR with at least 70% of ...
Characteristics and Outcomes of Patients With Cerebral Venous Sinus Thrombosis ...
Sánchez van Kammen, M; Aguiar de Sousa, D; Poli, S; Cordonnier, C; Heldner, M; van de Munckhof, A; Krzywicka, K; van Haaps, T; Ciccone, A; Middeldorp, SImportance: Thrombosis with thrombocytopenia syndrome (TTS) has been reported after vaccination with the SARS-CoV-2 vaccines ChAdOx1 nCov-19 (Oxford-AstraZeneca) and Ad26.COV2.S (Janssen/Johnson & Johnson). Objective: To describe the clinical characteristics and outcome of patients with cerebral venous sinus thrombosis (CVST) after SARS-CoV-2 vaccination with and without TTS. Design, setting, and participants: ...
Diferenças de Género no Tratamento de Fase Aguda do Acidente Vascular Cerebral ...
Taulaigo, A; Pedro, B; Mariano, M; Paiva Nunes, AIntroduction: In order to personalize stroke treatment, it is important to know if there are differences between genders in clinical features, acute phase treatment and outcomes. Material and Methods: Longitudinal retrospective study that included patients with ischemic stroke, admitted in a stroke unit during a 30 months period and treated with throm bectomy with or without thrombolysis. The objective was to a...
Mechanical Thrombectomy in Stroke in Nonagenarians: Useful or Futile?
Mendes Pinto, M; Paiva Nunes, A; Alves, M; Papoila, AL; Pamplona, J; Carvalho, R; Baptista, M; Reis, J; Fragata, IBackground: Mechanical thrombectomy is the standard treatment in acute ischemic stroke due to large vessel occlusion, but there is limited evidence about its efficacy in very old patients. We sought to analyse safety and effectiveness of mechanical thrombectomy in nonagenarian versus octagenarian patients. Methods: We included consecutive patients with acute ischemic stroke due to large vessel occlusion subject...
Dabigatran Initiation in Patients with Non-Valvular AF and First Acute Ischaemi...
Escudero-Martinez, I; Mazya, M; Teutsch, C; Lesko, N; Gdovinova, Z; Barbarini, L; Fryze, W; Karlinski, M; Kobayashi, A; Krastev, G; Paiva Nunes, ABackground and objective: The optimal timing for initiation of dabigatran after acute ischaemic stroke (AIS) is not established. We aimed to evaluate initiation timing and clinical outcomes of dabigatran in AIS patients with non-valvular atrial fibrillation (NVAF). Design: Retrospective study based on prospectively collected data in SITS (Safe Implementation of Treatment in Stroke) Thrombolysis and Thrombectomy...
Venous and Arterial TNF-R1 Predicts Outcome and Complications in Acute Subarach...
Fragata, I; Bustamante, A; Penalba, A; Ferreira, P; Paiva Nunes, A; Canhão, P; Montaner, JBackground: There is increasing evidence for the role of inflammation in clinical outcome after subarachnoid hemorrhage (SAH). Specifically, the TNF-alfa(α) pathway seems to be relevant after SAH. Although the TNF-α main receptor, TNF-R1 is associated with aneurysm growth and rupture, its relation to prognosis is unknown. We sought to compare TNF-R1 levels in peripheral venous blood and arterial blood closer to...