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The cerebellum is causally involved in episodic memory under aging

Almeida, Armando; Martins, Ana R.; Amaral, Lénia; Valério, Daniela; Bukhari, Qasim; Schu, Guilherme; Nogueira, Joana; Spínola, Mónica

Episodic memory decline is a major signature of both normal and pathological aging. Many neural regions have been implicated in the processes subserving both episodic memory and typical aging decline. Here, we demonstrate that the cerebellum is causally involved episodic memory under aging. We show that a 12-day neurostimulation program delivered to the right cerebellum led to improvements in episodic memory pe...


Digitalized transcranial electrical stimulation: a consensus statement

Brunoni, André R.; Ekhtiari, Hamed; Antal, Andrea; Auvichayapat, Paradee; Baeken, Chris; Benseñor, Isabela M; Bikson, Marom; Boggio, Paulo

Objective: Although relatively costly and non-scalable, non-invasive neuromodulation interventions are treatment alternatives for neuropsychiatric disorders. The recent developments of highly-deployable transcranial electric stimulation (tES) systems, combined with mobile-Health technologies, could be incorporated in digital trials to overcome methodological barriers and increase equity of access. The study aim...


Digitalized transcranial electrical stimulation: a consensus statement

Brunoni, Andre R; Ekhtiari, Hamed; Antal, Andrea; Auvichayapat, Paradee; Baeken, Chris; Benseñor, Isabela M; Bikson, Marom; Boggio, Paulo

Objective: Although relatively costly and non-scalable, non-invasive neuromodulation interventions are treatment alternatives for neuropsychiatric disorders. The recent developments of highly-deployable transcranial electric stimulation (tES) systems, combined with mobile-Health technologies, could be incorporated in digital trials to overcome methodological barriers and increase equity of access. The study aim...



Evidence-based guidelines and secondary meta-analysis for the use of transcrani...

Fregni, Felipe; El-Hagrassy, Mirret M.; Pacheco-Barrios, Kevin; Carvalho, Sandra; Leite, Jorge; Simis, Marcel; Brunelin, Jerome

Transcranial direct current stimulation (tDCS) has shown promising clinical results, leading to increased demand for an evidence-based review on its clinical effects. Objective We convened a team of tDCS experts to conduct a systematic review of clinical trials with more than one session of stimulation testing: Pain, Parkinson’s Disease Motor Function and Cognition, Stroke Motor Function and Language, Epilepsy,...


Evidence-based guidelines and secondary meta-analysis for the use of transcrani...

Fregni, Felipe; El-Hagrassy, Mirret M.; Pacheco-Barrios, Kevin; Carvalho, Sandra; Leite, Jorge; Simis, Marcel; Brunelin, Jerome

Background: Transcranial direct current stimulation has shown promising clinical results, leading to increased demand for an evidence-based review on its clinical effects. Objective: We convened a team of transcranial direct current stimulation experts to conduct a systematic review of clinical trials with more than 1 session of stimulation testing: pain, Parkinson’s disease motor function and cognition, stroke...


Popular stroke knowledge in Brazil: A multicenter survey during “World Stroke Day”

Gomes, Ana Beatriz Ayroza Galvão Ribeiro; Kubota, Gabriel Taricani; Araújo, Haniel Alves; Silva, Letícia Sant' Ana Cardosoda; Simis, Marcel

Made available in DSpace on 2019-09-11T20:51:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2017; Context and objective Cerebrovascular disease is one of the most important causes of death and disability worldwide. The patient's inability to identify the warning signs of stroke substantially delays the search for emergency services, which is related directly to a worse outcome. Thus, during the 2011 Strok...

Date: 2019   |   Origin: Oasisbr

Estimulação cerebral não-invasiva na prática clí­nica: atualização / Non-invasi...

Cavenaghi, Vitor Breseghello; Serafim, Vitor; Santos, Michele Devido dos; Simis, Marcel; Fregni, Felipe; Gagliardi, Rubens José

As técnicas de estimulação cerebral não-invasivas, sobretudo a estimulação magnética transcraniana (EMT) e a estimulação transcraniana por corrente contí­nua (ETCC), têm chamado a atenção de pesquisadores e profissionais da área da saúde, fato demonstrado pelo expressivo aumento no número de publicações sobre o assunto nos últimos anos. O objetivo deste artigo é, portanto, apresentar uma atualização sobre estim...

Date: 2018   |   Origin: Oasisbr

Median nerve stimulation induced motor learning in healthy adults: A study of t...

Carvalho, Sandra; French, Melanie; Thibaut, Aurore; Lima, Wilrama; Simis, Marcel; Leite, Jorge; Fregni, Felipe

Median nerve stimulation (MNS) has been shown to change brain metaplasticity over the somatosensory networks, based on a bottom-up mechanism and may improve motor learning. This exploratory study aimed to test the effects of MNS on implicit and explicit motor learning as measured by the serial reaction time task (SRTT) using a double-blind, sham-controlled, randomized trial, in which participants were allocated...


Neuromodulation as a cognitive enhancement strategy in healthy older adults: pr...

Martins, Ana R. S.; Fregni, Felipe; Simis, Marcel; Almeida, Jorge

Increases in life expectancy have been followed by an upsurge of age-associated cognitive decline. Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have risen as promising approaches to prevent or delay such cognitive decline. However, consensus has not yet been reached about their efficacy in improving cognitive functioning in healthy older adults. Here we review the e...


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