8 documents found, page 1 of 1
Iodine supplementation for pregnancy in Portugal: identification of nutritional...
Machado, SI; Roque, S; Lopes-Pereira, M; Costeira, MJ; Costa, P; Borges, Nuno; Pereira, R; Mendes, Z; Rodrigues, AT; Palha, JABackground Iodine is essential for the proper development of the central nervous system. In Portugal, despite of self-reports of iodine supplements intake by pregnant women, iodine deficiency still prevails. This study intended to characterize the pharmacy sales of iodine-containing supplements and their use by women in Portugal.Methods Data from all available supplements with indication for use in the prenatal...
Assessing Cognitive Function in Older Adults Using a Videoconference Approach
Castanho, TC; Amorim, L; Moreira, PS; Mariz, J; Palha, JA; Sousa, N; Santos, NCBACKGROUND: The use of communication technologies is an emerging trend in healthcare and research. Despite efficient, reliable and accurate neuropsychological batteries to evaluate cognitive performance in-person, more diverse and less expensive and time consuming solutions are needed. Here we conducted a pilot study to determine the applicability of a videoconference (VC, Skype®) approach to assess cognitive f...
Effector memory CD4(+) T cells are associated with cognitive performance in a s...
Serre-Miranda, C; Roque, S; Santos, NC; Portugal-Nunes, C; Costa, P; Palha, JA; Sousa, N; Correia-Neves, MOBJECTIVE: Immunosenescence and cognitive decline are common markers of the aging process. Taking into consideration the heterogeneity observed in aging processes and the recently described link between lymphocytes and cognition, we herein explored the possibility of an association between alterations in lymphocytic populations and cognitive performance. METHODS: In a cohort of cognitively healthy adults (n = 1...
The role of sex and sex-related hormones in cognition, mood and well-being in o...
Castanho, TC; Moreira, PS; Portugal-Nunes, C; Novais, A; Costa, PS; Palha, JA; Sousa, N; Santos, NCAlterations in hormone levels during aging impact on cognition and mood. Serum concentration levels of testosterone (TT), estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH), dehydroepiandrosterone sulfate (DHEAS) and prolactin (PRL) were assessed in 120 community-dwellers (51+ years of age, males and females), in a cross-sectional approach. Performance clusters based on executive funct...
Plasticity of resting state brain networks in recovery from stress
Soares, JM; Sampaio, A; Marques, P; Ferreira, LM; Santos, NC; Marques, F; Palha, JA; Cerqueira, JJ; Sousa, NChronic stress has been widely reported to have deleterious impact in multiple biological systems. Specifically, structural and functional remodeling of several brain regions following prolonged stress exposure have been described; importantly, some of these changes are eventually reversible. Recently, we showed the impact of stress on resting state networks (RSNs), but nothing is known about the plasticity of ...
Stress Impact on Resting State Brain Networks
Soares, JM; Sampaio, A; Ferreira, LM; Santos, NC; Marques, PS; Marques, F; Palha, JA; Cerqueira, JJ; Sousa, NResting state brain networks (RSNs) are spatially distributed large-scale networks, evidenced by resting state functional magnetic resonance imaging (fMRI) studies. Importantly, RSNs are implicated in several relevant brain functions and present abnormal functional patterns in many neuropsychiatric disorders, for which stress exposure is an established risk factor. Yet, so far, little is known about the effect ...
Cortical maturation in fetuses referred for ‘isolated’ mild ventriculomegaly: a...
Miguelote, RF; Vides, B; Santos, RF; Palha, JA; Matias, A; Sousa, NOBJECTIVES: To compare cortical maturation between fetuses with isolated mild ventriculomegaly (IMV) and healthy fetuses, and to explore its potential prognostic value in IMV. METHODS: This prospective study quantified cortical maturation by ultrasound in 24 fetuses with IMV and 46 healthy fetuses. Depth and grading the developmental pattern of the parieto-occipital fissure (POF), calcarine fissure (CF) and syl...
Revisiting thyroid hormones in schizophrenia
Santos, NC; Costa, P; Ruano, D; MacEdo, A; Soares, MJ; Valente, J; Pereira, AT; Azevedo, MH; Palha, JAThyroid hormones are crucial during development and in the adult brain. Of interest, fluctuations in the levels of thyroid hormones at various times during development and throughout life can impact on psychiatric disease manifestation and response to treatment. Here we review research on thyroid function assessment in schizophrenia, relating interrelations between the pituitary-thyroid axis and major neurosign...