94 documents found, page 1 of 10

Medicina: ciência, educação e inovação ao “serviço da vida humana”

[Excerto] Escola, desde sempre, se apresentou como um espaço de liberdade e diversidade que fomenta a curiosidade e a produção de conhecimento, conferindo autonomia científica, técnica e profissional a todos os que nela se formam e diferenciam. Esta Escola representa, a todos os níveis, um marco inovador na formação médica, primando pela excelência, não só nos eixos de atividade tradicionais – pedagógico, cient...

Prenatal supplements in Portugal: Iodine availability from pharmacy dispenses

Iodine availability through iodized salt in Portugal: 2010-2021 sales evolution...

Salt iodization programs are considered the most cost-effective measures to ensure adequate iodine intake in iodine-deficient populations. Portuguese women of childbearing age and pregnant women were reported to be iodine-deficient, which led the health authorities, in 2013, to issue a recommendation for iodine supplementation during preconception, pregnancy and lactation. In the same year, iodized salt became ...

Iodine Availability from Iodized salt sales from 2010 TO 2021: Evolution And Di...

Iodine supplementation: compliance and association with adverse obstetric and n...

Objectives: Over 1.9 billion people worldwide are living in areas estimated to be iodine insufficient. Strategies for iodine supplementation include campaigns targeting vulnerable groups, such as women in pre-conception, pregnancy and lactation. Portuguese women of childbearing age and pregnant women were shown to be mildly-to-moderately iodine deficient. As a response, in 2013, the National Health Authority (N...

Iron status is associated with mood, cognition, and functional ability in older...

Several conditions are risk factors for iron deficiency (ID), some of which are highly prevalent in older individuals. Despite the amount of evidence pointing for a role of ID in cognition, mood and physical functional ability, the research addressing these associations in older individuals is still scarce. In the present study, 162 older community-dwelling individuals (29.53% classified as ID) were enrolled in...

Impact of iodine supplementation during preconception, pregnancy and lactation ...

Background: Iodine deficiency is the most common cause of preventable brain harm and cognitive impairment in children. Portuguese women of childbearing age, pregnant women and their progeny were shown to have inadequate iodine intake. Consequently, the Portuguese Health Authorities have recommended a daily supplementation with 150-200 µg iodine in preconception, pregnancy, and lactation. The IodineMinho study i...

Proinflammatory and anti-inflammatory cytokines in the CSF of patients with Alz...

Cumulative data suggest that neuroinflammation plays a prominent role in Alzheimer's disease (AD) pathogenesis. The purpose of this work was to assess if patients with AD present a specific cerebrospinal fluid (CSF) cytokine profile and if it correlates to disease progression. We determined the levels of 27 cytokines in CSF of patients with AD and compared them with patients with frontotemporal dementia and non...

25-OH vitamin D levels and cognitive performance: longitudinal assessment in a ...

Background: Declining serum levels of 25-hydroxyvitamin D [25(OH)D, a biomarker of vitamin D status] with aging is a well-recognized phenomenon. However, scarce information is available on the relation between 25(OH)D levels and cognitive performance over time in older individuals. Our purpose was to evaluate, longitudinally, the association of 25(OH)D with cognitive function in a healthy older adults' cohort. ...

Structural and molecular correlates of cognitive aging in the rat

Aging is associated with cognitive decline. Herein, we studied a large cohort of old age and young adult male rats and confirmed that, as a group, old  rats display poorer spatial learning and behavioral flexibility than younger adults. Surprisingly, when animals were clustered as good and bad performers, our data revealed that while in younger animals better cognitive performance was associated with longer den...