Context - The rectal distension in dogs increases the rate of transitory lower esophageal sphincter relaxation considered the main factor causing gastroesophageal reflux. Objective - The aim of this study was evaluate the participation of the nitrergic pathway in the increased transitory lower esophageal sphincter relaxation rate induced by rectal distension in anesthetized dogs. Methods - Male mongrel dogs (n ...
Aims: We previously reported that mechanical atrial stretch (AS) by balloon distention increased gastric tonus in anesthetized rats. The present study evaluated the effect of AS on the gastric emptying of a liquid test meal in awake rats and its underlying neural mechanisms. Main methods: Anesthetizedmale rats received a balloon catheter into the right atrium and a gastrostomy cannula. The next day,mean arteria...
Arteriovenous (AV) anastomoses disrupt cardiovascular and renal homeostasis, 25 eliciting hemodynamic adjustments, resetting the humoral pattern, and inducing cardiac 26 hypertrophy. Because acute circulatory imbalance alters gut motor behavior, we studied the 27 effects of AV fistula placement on the gastric emptying (GE) of a liquid meal in awake rats. After 28 laparotomy, we created an aortocaval fistula (AC...
Right atrium mechanical stretch (AS) increases gastric motility in anesthetized rats. We aimed to study the effect of AS on gastric emptying (GE) in awake rats and the related neuro-humoral pathways ivolved. Male albino rats (N=361, 250-280g) had a silicone balloon inserted in the right atrium. After 24-h, the central venous pressure (CVP), heart rate (HR) and the mean arterial pressure (MAP) were monitored and...
PALHETA JÚNIOR, R. C. A distensão mecânica atrial direita diminui a complacência gástrica em ratos normovolêmicos anestesiados. 2006. 91 f. Dissertação (Mestrado em Farmacologia) - Universidade Federal do Ceará. Faculdade de Medicina, Fortaleza, 2006.; Graça et al. (2002) observou em ratos que a hipervolemia aumenta o tônus gástrico, enquanto a hipovolemia o diminuía. Resolvemos estudar o efeito do estiramento ...