2 documents found, page 1 of 1
Relationship of Demoralization With Anxiety, Depression, and Quality of Life: a...
Nanni, MG; Caruso, R; Travado, L; Ventura, C; Palma, A; Berardi, A; Meggiolaro, E; Ruffilli, F; Martins, C; Kissane, D; Grassi, LBackground: Demoralization syndrome is a significant condition that has not been greatly studied in Southern European countries. Aims: To extend the knowledge of demoralization in Southern Europe by examining its prevalence according to different methods of assessment, its relationship with anxiety and depression, and its impact on quality of life (QoL) among cancer patients. Methods: A convenience sample of 19...
Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glyca...
Loureiro, L; Sousa, D; Ferreira, D; Chai, W; Lima, L; Pereira, C; Lopes, C; Correia, V; Silva, L; Li, C; Santos, L; Ferreira, JA; Barbas, A; Palma, AIncomplete O-glycosylation is a feature associated with malignancy resulting in the expression of truncated glycans such as the sialyl-Tn (STn) antigen. Despite all the progress in the development of potential anti-cancer antibodies, their application is frequently hindered by low specificities and cross-reactivity. In this study, a novel anti-STn monoclonal antibody named L2A5 was developed by hybridoma techno...