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Neofiscalin A and fiscalin C are potential novel indole alkaloid alternatives f...

Bessa, Lucinda J.; Buttachon, Suradet; Dethoup, Tida; Martins, Rosario; Vasconcelos, Vitor; Kijjoa, Anake; Martins da Costa, Paulo

Ten indole alkaloids were obtained from the marine sponge-associated fungus Neosartorya siamensis KUFA 0017. We studied the antimicrobial properties of these and of three other compounds previously isolated from the soil fungus N. siamensis KUFC 6349. Only neofiscalin A showed antimicrobial activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resis...

Date: 2016   |   Origin: Repositório Científico do Instituto Politécnico do Porto
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