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Whole-genome sequencing of European autochthonous and commercial pig breeds all...

Bovo, S.; Ribani, A.; Muñoz, M.; Alves, E.; Araujo, J.P.; Bozzi, R.; Čandek-Potokar, M.; Charneca, R; Palma, F.D.; Etherington, G.; Fernandez, A.I.

Background: Natural and artificial directional selection in cosmopolitan and autochthonous pig breeds and wild boars have shaped their genomes and resulted in a reservoir of animal genetic diversity. Signatures of selection are the result of these selection events that have contributed to the adaptation of breeds to different environments and production systems. In this study, we analysed the genome variability...


Genome-wide detection of copy number variants in European autochthonous and com...

Bovo, S.; Ribani, A.; Muñoz, M.; Alves, E.; Araujo, J.P.; Bozzi, R.; Charneca, R.; Palma, F.D.; Etherington, G.; Fernandez, A.I.; García, F.

In this study, we identified copy number variants (CNVs) in 19 European autochthonous pig breeds and in two commercial breeds (Italian Large White and Italian Duroc) that represent important genetic resources for this species. The genome of 725 pigs was sequenced using a breed-specific DNA pooling approach (30–35 animals per pool) obtaining an average depth per pool of 429. This approach maximised CNV discovery...


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