642 documents found, page 1 of 65
Omega-3 and conjugated fatty acids impact on human microbiota modulation using ...
Salsinha, Ana Sofia; Araújo-Rodrigues, Helena; Dias, Cindy; Cima, André; Rodríguez-Alcalá, Luís Miguel; Relvas, João B.; Pintado, ManuelaBackground& aims: Gut microbiota has been gaining increasing attention and itsimportant role in the maintenance of a general good health condition is alreadyestablished. The potential of gut microbiota modulation through diet is animportant research focus to be considered. Lipids, as omega-3 fatty acids, arewell known for their beneficial role on organs and corresponding diseases.However, their impact on gut mi...
Inclusion of pineapple by-products as natural antioxidant sources in diets for ...
Pereira, Ricardo; Basto, Ana; Pintado, Manuela; Valente, Luisa M. P.; Velasco, CristinaThis study investigates the effects of pineapple by-products on feed preservation during storage at two different temperatures (25 °C and 4 °C) and on European sea bass (Dicentrarchus labrax) stress resistance. Four isoproteic, isolipidic, and isoenergetic diets were manufactured: CTRL—negative control, commercial diet without added antioxidants; VITE—positive control, CTRL diet with 100 mg kg−1 of vitamin E; a...
Exploring the effects of sweet potato leaves on skin health - from antimicrobia...
Machado, Manuela; Silva, Sara; Pintado, Manuela; Costa, Eduardo M.Sweet potato leaves (SPL), an agricultural byproduct, hold significant potential in dermatological applications due to their bioactive compounds. This study evaluates the phenolic profile of SPL extracts and investigates their biological activities relevant to skin health. Extract fingerprinting, through uHPLC-DAD and LC–MS, identified phenolic acids and flavonoids, with cynarin, neochlorogenic acid, and spirae...
Exploring the potential of mealworm chitosan for hemodialysis applications
Martingo, Maria; Baptista-Silva, Sara; Mesquita, Raquel; Ferreira, João Paulo; Borges, Sandra; Pintado, ManuelaThis study introduces a sustainable and efficient alternative to traditional chitosan sources derived from crustaceans, exploring the extraction and application of insect-derived chitosan from Tenebrio molitor for hemodialysis (HD) membranes design. Efficient extraction and deacetylation methods were tested and developed between 6 h and 12 h to obtain chitosan. Chitin was isolated from T. molitor through deprot...
Edible films with protein and bioactive compounds from arthrospira sp.
Martins, Valter F. R.; Poças, Fátima; Pintado, Manuela; Morais, Rui M. S. C.; Morais, Alcina M. M. B.Arthrospira sp. is an alternative source of protein in the food chain, but it may also be considered a source of phenolic compounds with interesting properties, such as antioxidant and antimicrobial properties. In active packaging, these two properties are essential. In the present work, two extracts were produced: one extract rich in protein and another in bioactives. These two extracts were used in the produc...
Breaking the virus: yeast glucans as an effective alternative to acyclovir in H...
Tavares-Valente, Diana; Moreira, Helena; Sousa, Pedro; Amorim, Manuela; Conde, António; Pintado, Manuela; Fernandes, João; Azevedo-Silva, JoãoGlucans, structural polysaccharides in the yeast cell wall, are known for their biological and immunomodulatory capacities, helping in prevention and management of infections. Herpes simplex virus type 1 (HSVI) is a prevalent infection that causes great comorbidity and is challenging to treat due to the adverse effects of standard antiviral drugs like acyclovir. This study assessed the potential of yeast glucan...
Exploring the bioactive potential of mushroom aqueous extracts: antimicrobial, ...
Afonso, Tiago Barros; Marçal, Sara; Vale, Pedro; Sousa, Ana Sofia; Nunes, João; Pintado, ManuelaMushrooms provide essential nutrients and bioactive compounds, namely glucans, protein, and phenolic compounds. In this study, two aqueous extractions were performed (M1 and M2) using Pleurotus ostreatus, Pleurotus eryngii, and Agrocybe cylindracea. In M1, a hot extraction (extract M1) (90 °C, 700 rpm, 1 h) was performed. In M2, a room-temperature extraction (extract M2A) followed by a hot extraction (extract M...
Prebiotic potential of olive leaf by-product throughout in vitro human colon fe...
Gutiérrez, Mónica Sánchez; Gómez-García, Ricardo; Pintado, Manuela; Rodríguez, Alejandro; Carrasco, ElenaOlive leaf represents a promising source of novel ingredients with potential health benefits, being rich in dietary fiber and phenolic compounds. This study aimed to evaluate the prebiotic effects of olive leaf bioactive compounds through in vitro human colonic fermentation. The phenolic compounds identified prior to fermentation included hydroxytyrosol, vanillin, oleuropein, and tyrosol. Olive ground leaf sign...
Valorization of Solanum melongena L. crop by-products: phenolic composition and...
Añibarro-Ortega, Mikel; Dias, Maria Inês; Petrović, Jovana; Núñez, Sonia; Calhelha, Ricardo C.; Costa, Eduardo M.; Machado, M.; Pintado, ManuelaThis study explored the valorization of post-harvest eggplant aerial parts as a sustainable source of value-added ingredients by investigating their phenolic composition and in vitro bioactive properties. HPLC-DAD-ESI/MSn analysis identified chlorogenic acid derivatives as the predominant phenolic compounds (53 % of the phenolic fraction), followed by O-glycosylated kaempferol and quercetin. The extract display...
Bioactive potential of olive leaf by-product throughout in vitro gastrointestin...
Sánchez-Gutiérrez, Mónica; Gómez-García, Ricardo; Carrasco, Elena; Rodríguez, Alejandro; Pintado, ManuelaOlive leaf, an abundant and underutilized byproduct of the olive industry, has gained attention as a potential functional ingredient due to its high content of dietary fiber and phenolic compounds. However, little is known about its bioaccessibility and transformation throughout the digestive process, limiting its application in food formulations. This study provides a comprehensive and quantitative assessment ...