2 documents found, page 1 of 1
First evidence of dermo-protective activity of marine sulfur-containing histidi...
Brancaccio, Mariarita; Milito, Alfonsina; S B Viegas, Carla; Palumbo, Anna; Simes, Dina; Castellano, ImmacolataAmong natural products, ovothiol (ovo), produced by marine invertebrates, bacteria, and microalgae, is receiving increasing interest for its unique antioxidant properties. Recently, ovo has been shown to exhibit anti-inflammatory activity in an in vitro model of endothelial dysfunction and in an in vivo model of liver fibrosis.The aim of this study was to evaluate the effect of ovo and its precursor 5-thiohisti...
Cephalopods in neuroscience: regulations, research and the 3Rs
Fiorito, Graziano; Affuso, Andrea; Anderson, David B; Basil, Jennifer; Bonnaud, Laure; Botta, Giovanni; Cole, Alison; D'Angelo, LiviaCephalopods have been utilised in neuroscience research for more than 100 years particularly because of their phenotypic plasticity, complex and centralised nervous system, tractability for studies of learning and cellular mechanisms of memory (e.g. long-term potentiation) and anatomical features facilitating physiological studies (e.g. squid giant axon and synapse). On 1 January 2013, research using any of the...