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Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials

Das, G; Shin, HS; Leyva-Gómez, G; Prado-Audelo, MLD; Cortes, H; Singh, YD; Panda, MK; Mishra, AP; Nigam, M; Saklani, S; Chaturi, PK; Martorell, M

In recent decades, interest in the Cordyceps genus has amplified due to its immunostimulatory potential. Cordyceps species, its extracts, and bioactive constituents have been related with cytokine production such as interleukin (IL)-1ß, IL-2, IL-6, IL-8, IL-10, IL-12, and tumor necrosis factor (TNF)-a, phagocytosis stimulation of immune cells, nitric oxide production by increasing inducible nitric oxide synthas...


Paclitaxel: Application in Modern Oncology and Nanomedicine-Based Cancer Therapy

Sharifi-Rad, J; Quispe, C; Patra, JK; Singh, YD; Panda, MK; Das, G; Adetunji, CO; Michael, OS; Sytar, O; Polito, L; Živkovic, J; Martins, N

Paclitaxel is a broad-spectrum anticancer compound, which was derived mainly from a medicinal plant, in particular, from the bark of the yew tree Taxus brevifolia Nutt. It is a representative of a class of diterpene taxanes, which are nowadays used as the most common chemotherapeutic agent against many forms of cancer. It possesses scientifically proven anticancer activity against, e.g., ovarian, lung, and brea...


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