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Quantification of tumor burden in multiple myeloma by atlas-based semi-automati...

Almeida, Sílvia D.; Santinha, João; Oliveira, Francisco P.M.; Ip, Joana; Lisitskaya, Maria; Lourenço, João; Uysal, Aycan; Matos, Celso; João, Cristina

BACKGROUND: Whole-body diffusion weighted imaging (WB-DWI) has proven value to detect multiple myeloma (MM) lesions. However, the large volume of imaging data and the presence of numerous lesions makes the reading process challenging. The aim of the current study was to develop a semi-automatic lesion segmentation algorithm for WB-DWI images in MM patients and to evaluate this smart-algorithm (SA) performance b...


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