Pathological complete response (pCR) to neoadjuvant chemotherapy (NAChT) has been validated as a predictor of long-term survival in breast cancer (BC), especially in triple-negative breast cancer (TNBC)
biomaterials for delivery of bioactive substances that can be controlled by external stimuli. Herein we report the production of smart partially biodegradable scaffolds that exhibit pH- and temperatureresponsive behavior and their effects on the release of a model protein and a drug of low molecular weight. Chitosan (CHT) scaffolds (pH sensitive) were coated/impregnated with a thermoresponsive polymer, poly(N-i...