3 documents found, page 1 of 1
Uso De Factores De Crescimento De Granulócitos: Recomendações da Sociedade Port...
Forjaz de Lacerda, J; Leal da Costa, F; Pereira, AM; Principe, F; Teixeira, A; Parreira, AThe administration of cytotoxic chemotherapy may be complicated by the emergence of neutropenia and febrile neutropenia, frequently determining hospital admission and intravenous treatment with broad spectrum antibiotics. Frequently, it is necessary to reduce the dose or to delay the administration of the cytotoxic drugs reducing the relative dose intensity of the chemotherapy regimen. Granulocyte growth factor...
The use of peripheral blood progenitor cells as an autologous hematopoietic sup...
Silva, M R; Passos-Coelho, J L; da Costa, F L; Machado, M A; Miranda, N; Miranda, M H; Parreira, AWe report the results of PBPC collection by large-volume leukaphereses and the hematologic recovery after high-dose chemotherapy supported by autologous PBPC reinfusion in a series of cancer patients treated at the Hematological Intensive Care Unit (UCHI) (Portuguese Institute of Oncology, Lisbon). Large volume leukaphereses were used to increase the efficacy of the PBPC collection. This modification of the sta...
The use of peripheral blood progenitor cells as an autologous hematopoietic sup...
Silva, M R; Passos-Coelho, J L; da Costa, F L; Machado, M A; Miranda, N; Miranda, M H; Parreira, AWe review the rationale for PBPC transplantation and the results reported in the literature. In order to prolong complete remissions and increase cure rates, high-dose chemotherapy is frequently used in the treatment of selected neoplasias. Hematological toxicity can be overcome by the infusion of autologous hemopoietic progenitors. Recently, peripheral blood is being used as the preferred source for hemopoieti...