4 documents found, page 1 of 1
Corrigendum: Evidence for a genetic contribution to the ossification of spinal ...
Couto, Ana Rita; Parreira, Bruna; Power, Deborah Mary; Pinheiro, Luís; Dias, João Madruga; Novofastovski, Irina; Eshed, Iris; Sarzi-Puttini, Piercarlo
The Role of Biobanks in the Fight against COVID-19 Pandemic: The Portuguese Res...
Abdulghani, Saba; Afonso, Ângela; Castillo, Mireia; Martín-Fernández, Javier; Franco, Inês; Parreira, Bruna; Couto, Ana; Bruges-Armas, JácomeN/a.; N/a.
Evidence for a genetic contribution to the ossification of spinal ligaments in ...
Couto, Ana Rita; Parreira, Bruna; Power, Deborah; Pinheiro, Luís; Madruga Dias, João; Novofastovski, Irina; Eshed, Iris; Sarzi-Puttini, PiercarloDiffuse Idiopathic Skeletal Hyperostosis (DISH) and Ossification of the Posterior Longitudinal Ligament (OPLL) are common disorders characterized by the ossification of spinal ligaments. The cause for this ossification is currently unknown but a genetic contribution has been hypothesized. Over the last decade, many studies on the genetics of ectopic calcification disorders have been performed, mainly on OPLL. M...
Persistence of the ABCC6 genes and the emergence of the bony skeleton in verteb...
Parreira, Bruna; Cardoso, João; Costa, Rita; Couto, Ana Rita; Bruges-Armas, Jacome; Power, Deborah M.The ATP-binding cassette transporter 6 (ABCC6) gene encodes a cellular transmembrane protein transporter (MRP6) that is involved in the regulation of tissue calcification in mammals. Mutations in ABCC6 are associated with human ectopic calcification disorders. To gain insight into its evolution and involvement in tissue calcification we conducted a comparative analysis of the ABCC6 gene and the related gene ABC...