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Investigating maternal-fetal interface in the context of obesity using trophobl...

Parreira, Denise

A incidência de obesidade aumentou exponencialmente na última década, tendo sido considerada pela Organização Mundial de Saúde como epidemia. Mulheres grávidas com obesidade são mais susceptíveis a complicações na gravidez, frequentemente resultado de problemas no desenvolvimento da placenta. Contudo, o processo molecular subjacente aos efeitos da obesidade no desenvolvimento da placenta permanece elusivo. O no...


Genome-wide identification, phylogeny, and gene duplication of the epigenetic r...

Alves, Sofia; Braga, Ângelo; Parreira, Denise; Alhinho, Ana Teresa; Silva, Helena Sofia Gomes; Ramos, Miguel Jesus Nunes; Costa, Maria Manuela Ribeiro

Epigenetic regulators are proteins involved in controlling gene expression. Information about the epigenetic regulators within the Fagaceae, a relevant family of trees and shrubs of the northern hemisphere ecosystems, is scarce. With the intent to characterize these proteins in Fagaceae, we searched for orthologs of DNA methyltransferases (DNMTs) and demethylases (DDMEs) and Histone modifiers involved in acetyl...


Genome-wide identification, phylogeny, and gene duplication of the epigenetic r...

Alves, Sofia; Braga, Angelo; Parreira, Denise; Alhinho, Ana Teresa; Silva, Helena; Ramos, Miguel Jesus Nunes; Costa, Maria Manuela Ribeiro

Epigenetic regulators are proteins involved in controlling gene expression. Informationabout the epigenetic regulators within the Fagaceae, a relevant family of trees andshrubs of the northern hemisphere ecosystems, is scarce. With the intent to character-ize these proteins in Fagaceae, we searched for orthologs of DNA methyltransferases(DNMTs) and demethylases (DDMEs) and Histone modifiers involved in acetylat...


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