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Core Curriculum in Headaches for Neurologists: Proposal from the Portuguese Hea...

Parreira, Elsa; Machado, Sara; Gil-Gouveia, Raquel

Continuous education in headaches is a priority for the Portuguese Headache Society. We present a proposal for a Core Curriculum in Headaches for Neurologists and Neurology-trainees, developed based on the ‘Headache Core Curriculum’ of the International Headache Society (IHS), revised in May 2020. This document is not merely a translation of the original but rather a structured adaptation to the national contex...

Date: 2025   |   Origin: SINAPSE

International Classification of Orofacial Pain: Portuguese Translation (2024)

Parreira, Elsa; Fonseca, Júlio; Brás, Alice; Pereira, Joana; Pereira, Liliana; Oliveira, Renato; Moutinho, Rita; Machado, Sara

The new International Classification of Orofacial Pain (ICOP) (1st Edition), a joint venture of the International Headache Society, American Academy of Orofacial Pain (AAOP), Orofacial and Head Pain Special Interest Group (OFHP SIG) of the International Association for the Study of Pain (IASP) and International Network for Orofacial Pain and Related Disorders Methodology (INfORM), lists all causes of orofacial ...

Date: 2025   |   Origin: SINAPSE

Gestão das cefaleias em Portugal: consenso das Sociedades Portuguesas de cefale...

Gil-Gouveia, Raquel; Parreira, Elsa; Martins, Isabel Pavão; Luzeiro, Isabel; Pereira, Raúl Marques; Plácido, Madalena; Palavra, Filipe

As cefaleias são uma causa significativa de incapacidade a nível global, com a enxaqueca a ocupar o segundo lugar entre as doenças com mais anos vividos com incapacidade. A maioria dos doentes com cefaleias, incluindo enxaqueca, podem e devem ser diagnosticados, tratados e acompanhados eficazmente nos cuidados de saúde primários. Isso não só reduz a incapacidade associada a estas patologias, mas também previne ...


Currículo básico em cefaleias para neurologistas: proposta da Sociedade Portugu...

Parreira, Elsa; Machado, Sara; Gil-Gouveia, Raquel

Continuous education in headaches is a priority for the Portuguese Headache Society. We present a proposal for a Core Curriculum in Headaches for Neurologists and Neurology-trainees, developed based on the ‘Headache Core Curriculum’ of the International Headache Society (IHS), revised in May 2020. This document is not merely a translation of the original but rather a structured adaptation to the national contex...


Cluster Headache Secondary to Trauma Presenting with Unilateral Mydriasis

Gonçalo Pinheiro, Rita; Peres, João; Tojal, Raquel; Parreira, Elsa

Cluster headache is the most common trigeminal autonomic cephalalgia, it can be a primary or secondary headache. Attacks are frequently associated with autonomic symptoms, due to parasympathetic activation and sympathetic defect. An 86-year-old woman, with no previous history of headache, developed a right supraorbital headache, two weeks after a fall, that resulted in mild head trauma to the ipsilateral fronta...

Date: 2024   |   Origin: SINAPSE

Chronic and Refractory Migraine: How to Diagnose and Treat

Parreira, Elsa; Luzeiro, Isabel; Pereira Monteiro, José Maria

Migraine is highly prevalent and carries a significant personal, social and economic burden. It is the second cause of disability (years living with disability) worldwide and the first cause under 50 years of age. Chronic migraine (occurring for more than 15 days a month) and refractory migraine (treatment resistant), especially when there is also analgesic overuse, are the most disabling forms of migraine. The...

Date: 2020   |   Origin: Acta Médica Portuguesa

PROS1 novel splice site variant decreases protein S expression in patients from...

Menezes, Juliane; Ventura, Célia; Matos Costa, João; Parreira, Elsa; Romão, Luísa; Gonçalves, João

Protein S (PS) is a widely studied protein with an important function in the downregulation of thrombin formation. Since its discovery in 1976, more than 400 variants have been described in PS gene (PROS1) associated with PS deficiency and as a risk factor for venous thromboembolism (VTE). We describe a novel variant, c.1871-14T>G, in intron 14 of PROS1 gene identified in two patients with PS deficiency from tw...


Cluster headache: Pathophysiology, clinical presentation and treatment

Parreira, Elsa; Gouveia, Raquel Gil; Martins, Isabel Pavão

A cluster headache is within the primary headaches, which presents the most characteristic clinical constellation, making diagnosis very affordable. However, given its rarity, this entity is often ignored by clinicians in the differential diagnosis of headache. The importance of proper diagnosis is essential because this violent headache has a particular therapeutic approach and usually quite effective. In this...


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