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Loss of antiphospholipid antibody positivity decreases the risk of recurrent th...

Gaspar, Pedro; Cruz-Machado, Ana Rita; Abrantes, Ana Mafalda; Costa, Filipa; Parreira, Inês; Lopes, Ana Rita; Costa-Silva, Ryan; Chícharo, Ana Teodósio

OBJECTIVE: To establish the predictive value of antiphospholipid antibody (aPL) negativization on recurrent thrombosis in thrombotic antiphospholipid syndrome (APS). METHODS: Retrospective cohort study including all consecutive adult patients with APS followed at Hospital de Santa Maria, Lisbon, Portugal, up to December 2024. At diagnosis, all patients were positive for solid-phase aPL. Then, patients were cate...


Esofágo Negro: Um Caso de Hemorragia Digestiva Alta em Doente Diabética

Parreira, Inês; Santos, Carolina António; Alves Cardoso, Ana

Date: 2025   |   Origin: SPMI Case Reports

Calcificação Caseosa: Um Achado Ecográfico Inesperado

António Santos, Carolina; Cardoso, Ana; Parreira, Inês

Date: 2025   |   Origin: SPMI Case Reports

Predictors of Long-COVID-19 and its Impact on Quality of Life: Longitudinal Ana...

Gaspar, Pedro; Dias, Mariana; Parreira, Inês; Gonçalves, Hélder Diogo; Parlato, Federica; Maione, Valeria; Atalaia Barbacena, Henrique

Introduction: Long-COVID-19 impacts health-related quality of life (HR-QoL) but data is scarce. The aim of this study was to describe and prospectively assess the prevalence and risk factors for long-COVID-19 after hospital discharge, and to evaluate its impact on patient HR-QoL.Methods: Single-centre longitudinal study including all COVID-19 patients discharged between December 2020 and February 2021. Patients...

Date: 2023   |   Origin: Acta Médica Portuguesa

Phenotype of BTK‐lacking myeloid cells during prolonged COVID‐19 and upon conva...

Gomes, André; Farias, Guilherme B.; Trombetta, Amelia Chiara; Godinho-Santos, Ana; Parreira, Inês; Gonçalves, Hélder Diogo; Lessa Simões, Mariana

XLA patient with 7-month course of COVID-19 with persistent plasma SARS-CoV-2 load revealed a sustained non-inflammatory profile of myeloid cells in association with contained severity of disease, arguing in favor of the use of BTK inhibitors in SARS-COV-2 infection.


Demographic Characterization, Clinical Course and Risk Factors for Mortality of...

Antunes Meireles, Pedro; Gaspar, Pedro; Parreira, Inês; Abrantes, Ana Mafalda; Dias Silva, Virgílio; Bessa, Filipe; Pais de Lacerda, António

Introduction: Clinical characteristics of Portuguese inpatients with coronavirus disease 2019 (COVID-19) are scarce. We aim to describe the demographic characteristics, clinical course and outcomes of hospitalized patients with COVID-19 and to analyze risk factors for in-hospital mortality. Material and Methods: Ambispective cohort study of adult COVID-19 patients admitted to a Portuguese tertiary hospital betw...


Acalculous acute pancreatitis in a COVID-19 patient

Meireles, Pedro Antunes; Bessa, Filipe; Gaspar, Pedro; Parreira, Inês; Silva, Virgílio Dias; Mota, Catarina; Alvoeiro, Lourdes

Coronavirus disease 2019 (COVID-19) is a multisystemic condition caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) with manifestations ranging from mild upper respiratory symptoms to cytokine storm causing acute respiratory distress syndrome. Pancreatic exocrine tissue and endocrine islets both express angiotensin-converting enzyme 2 (ACE2), the proven receptor for SARSCoV-2 cell internaliza...


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