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The Impact of Lung Carcinoma Histology on the Frequency of Bone Metastases
Oliveira,Marcelo Bragança dos Reis; Souza,Larissa Costa; Sampayo,Ermides Javier Garcia; Carvalho,Gustavo Sobral de; Mello,Fernanda Carvalho de QueirozAbstract Objective Lung cancer is the leading cause of death by cancer, and the bones are one of the most common sites of metastasis from this condition. This study aimed to evaluate the influence of lung carcinoma histology on the frequency of bone metastases. Methods This retrospective study evaluated the medical records of 407 patients diagnosed with lung cancer between 2003 and 2012. The prevalence of bone ...
PERCUTANEOUS TREATMENT OF ANEURYSMAL BONE CYST WITH CALCITONIN AND METHYLPREDNI...
Oliveira,Marcelo Bragança dos Reis; Meohas,Walter; Silva,Ronan Ribeiro; Carvalho,Gustavo Sobral de; Mello,Fernanda Carvalho de QueirozABSTRACT Objective: To introduce the intralesional calcitonin and methylprednisolone percutaneous injection method, which results in the promotion of primary aneurysmal bone cyst (ABC) healing. Methods: A retrospective cohort study involving 76 patients diagnosed with ABC was performed between 2005 and 2014. Patients treated with calcitonin and methylprednisolone injection and who underwent more than 2 years of...
PATHOLOGICAL FRACTURES DUE TO BONE METASTASES FROM LUNG CANCER: RISK FACTORS AN...
Oliveira,Marcelo Bragança dos Reis; Marques,Bruno de Carvalho; Matos,Rosa Aurílio; Fontenelle,César Rubens da Costa; Mello,Fernanda Carvalho de QueirozABSTRACT Introduction: Pathological fractures are frequent skeletal-related events among lung cancer patients, which result in high morbidity and decreased overall survival and make operative treatment decisions challenging. Objectives: To identify risk factors associated with the occurrence of pathological fractures in patients with lung cancer and to determine survival. Methods: We conducted a retrospective c...
Marcadores moleculares no câncer de pulmão: papel prognóstico e sua relação com...
Duarte,Ricardo Luiz de Menezes; Paschoal,Marcos Eduardo MachadoEstudos epidemiológicos têm demonstrado um nexo causal entre tabagismo e carcinoma de pulmão. Embora a maioria dos cânceres de pulmão esteja associada com tabagismo, somente uma minoria de grandes tabagistas desenvolve essa malignidade, o que leva ao conceito de que fatores genéticos afetam a susceptibilidade individual. As principais alterações moleculares no câncer de pulmão são: genes de supressão tumoral, p...