8 documents found, page 1 of 1
Gamificação no Ensino Superior: Simulação e Avaliação do Modelo “Exploradores d...
Pascoal, RuiThis article presents and evaluates, through simulation, a gamification model called “Knowledge Explorers”, developed for higher education. The model integrates game elements — such as academic missions, scoring systems, rewards, rankings and continuous feedback — into the curriculum of university courses, with the aim of promoting greater engagement, active learning and skill development. The simulation was co...
Price Appreciation and Roughness Duality in Bitcoin: A Multifractal Analysis
Vaz, Cristiana; Pascoal, Rui; Sebastião, HelderSince its launch in 2009, bitcoin has thrived, attracting the attention of investors, regulators, academia, and the public in general. Its price dynamics, characterized by extreme volatility, severe jumps, and impressive long-term appreciation, suggest that bitcoin is a new digital asset. This study presents a comprehensive overview of the fractality of bitcoin in a high-frequency framework, namely by applying ...
Firms’ performance and board size: A simultaneous approach in the European and ...
Augusto, Mário António Gomes; Pascoal, Rui; Reis, PedroThe relation between performance and board size is analyzed in the American and European contexts. It is found that return on assets (ROA) depends on board size (BS) defined as an endogenous explanatory variable. This potentially non-monotonous effect is modeled by introducing firm size and number of segments by board member as explanatory variables for ROA. BS net effect after accounting for the indirect effec...
Firms’ performance and board size: A simultaneous approach in the European and ...
Augusto, Mário; Pascoal, Rui; Reis, PedroThe relation between performance and board size (BS) is analysed in the American and European contexts. It is found that return on assets (ROA) depends on BS defined as an endogenous explanatory variable. This potentially non-monotonous effect is modelled by introducing firm size and number of segments by board member as explanatory variables for ROA. BS net effect after accounting for the indirect effect resul...
Addition of the Aβ42/40 ratio to the cerebrospinal fluid biomarker profile incr...
Baldeiras, Inês; Santana, Isabel; Leitão, Maria João; Gens, Helena; Pascoal, Rui; Tábuas-Pereira, Miguel; Beato-Coelho, José; Duro, DianaBackground: Cerebrospinal fluid (CSF) biomarkers have been used to increase the evidence of underlying Alzheimer’s disease (AD) pathology in mild cognitive impairment (MCI). However, CSF biomarker-based classification often results in conflicting profiles with controversial prognostic value. Normalization of the CSF Aβ42 concentration to the level of total amyloid beta (Aβ), using the Aβ42/40 ratio, has been sh...
Multiple sclerosis: Association of gelatinase B/matrix metalloproteinase-9 with...
Valado, Ana; Leitão, Maria João; Martinho, António; Pascoal, Rui; Cerqueira, João José; Correia, Inês; Batista, Sónia; Sousa, Lívia; Baldeiras, InêsBackground: Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation and axonal degeneration of the central nervous system and a leading cause of disability in young adults. The matrix metalloproteinases in general and specially gelatinase B/metalloproteinase-9 (MMP-9) plays a role in the pathogenesis of multiple sclerosis. Objective: To investigate the presence of the MMP-9 1562 C/T polym...
Market Efficiency, Roughness and Long Memory in PSI20 Index Returns: Wavelet an...
Pascoal, Rui; Monteiro, Ana MargaridaIn this study, features of the financial returns of the PSI20index, related to market efficiency, are captured using wavelet- and entropy-based techniques. This characterization includes the following points. First, the detection of long memory, associated with low frequencies, and a global measure of the time series: the Hurst exponent estimated by several methods, including wavelets. Second, the degree of rou...
Cigarette Smoking Increases Oxidative Stress in Prostate Cancer Patients – A Pr...
Freitas, Mariana; Baldeiras, Inês; Proença, Teresa; Pascoal, Rui; Rabaça, Carlos; Valido, Frederico; Mota-Pinto, Anabela; Sarmento-Ribeiro, Ana BelaCigarette smoke is an oxidant, creating free radicals that are involved in carcinogenesis namely in Prostate Cancer (PC). However, a correlation between cigarette smoking and PC progression remains unclear. This study was directed to evaluate the correlation between cigarette smoking, Oxidative Stress (OS) and PC development and progression. The Total Antioxidant Status (TAS), Glutathione (GSH) and Malondialdeh...