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Trypanocidal activity of Piper arboreum and Piper tuberculatum (Piperaceae)

Regasini,Luis Octávio; Cotinguiba,Fernando; Passerini,Gabriela Duó; Bolzani,Vanderlan da Silva; Cicarelli,Regina Maria Barretto; Kato,Massuo Jorge

In the scope of our ongoing research on bioactive agents from Brazilian flora, twenty-four extracts and fractions obtained from Piper arboreum Aub. and Piper tuberculatum Jacq. (Piperaceae) were screened for trypanocidal activity by using MTT colorimetric assay. The strongest activity was found in hexane fractions from the leaves of P. arboreum (IC50= 13.3 µg/ mL) and P. tuberculatum (IC50 = 17.2 µg/mL). Hexane...

Date: 2009 | Origin: Oasisbr

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