Made available in DSpace on 2022-04-28T19:43:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); A new biobased compound was prepared from commercially available monoterpene thymol, obtained from the...
Made available in DSpace on 2021-06-25T10:58:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; The production of ergosterol lipid involves the activity of different enzymes and is a crucial event for the Leishmania membrane homeostasis. Such enzymes can be blocked by azoles and allylamines drugs, such as the antifungal butenafine chloride. This drug was active on parasites that cause cutaneous an...
Made available in DSpace on 2018-11-26T15:37:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-11-18; Delaney AIDS Research Enterprise (DARE); NIAID; UCSF/Gladstone Institute of Virology & Immunology CFAR; UCSF Clinical and Translational Research Institute Clinical Research Center; Center for AIDS Prevention Studies; CFAR Network of Integrated Systems; NIH NIAID; Conselho Nacional de Desenvolvimento Cie...
Made available in DSpace on 2018-12-11T17:22:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-08-27. Added 1 bitstream(s) on 2021-07-15T15:22:08Z : No. of bitstreams: 1 S1678-91992018000100312.pdf: 922596 bytes, checksum: 18fb86fe456fe9c71e3e438fca44c19d (MD5); Background: Lipid metabolites play an important role in parasite differentiation and virulence. Studies have revealed that Leishmania sp. uses ...
Made available in DSpace on 2018-12-11T17:06:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The production of ergosterol lipid, important for the Leishmania membrane homeostasis, involves different enzymes. This pathway can be blocked to azoles and allylamines drugs, such as Butenafine. The aim of the present work was to evaluate t...
Made available in DSpace on 2018-12-11T17:08:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-04-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Leishmaniasis is an important neglected tropical disease, affecting more than 12 million people worldwide. The available treatments are not well tolerated and present diverse side effects in patients, justifying the search for new therapeuti...
Made available in DSpace on 2018-12-11T17:09:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-03-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The development of novel drugs for the treatment of leishmaniases continues to be crucial to overcome the severe impacts of these diseases on human and animal health. Seve...
Made available in DSpace on 2013-08-28T14:12:34Z (GMT). No. of bitstreams: 1 WOS000303445700001.pdf: 1329763 bytes, checksum: 12095f22f988429800896c72e7d84434 (MD5); Made available in DSpace on 2013-09-30T19:23:16Z (GMT). No. of bitstreams: 2 WOS000303445700001.pdf: 1329763 bytes, checksum: 12095f22f988429800896c72e7d84434 (MD5) WOS000303445700001.pdf.txt: 46234 bytes, checksum: 17f63beb0b5ac51dadbbb0405f8bf051...