15 documents found, page 1 of 2

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Polysaccharide-Based Carriers for Pulmonary Insulin Delivery: The Potential of ...

Valente, Sara A.; Lopes, Guido R.; Ferreira, Isabel; Galrinho, Miguel F.; Almeida, Margarida; Ferreira, Paula; Cruz, Maria T.; Coimbra, Manuel A.

Non-invasive routes for insulin delivery are emerging as alternatives to currently painful subcutaneous injections. For pulmonary delivery, formulations may be in powdered particle form, using carriers such as polysaccharides to stabilise the active principle. Roasted coffee beans and spent coffee grounds (SCG) are rich in polysaccharides, namely galactomannans and arabinogalactans. In this work, the polysaccha...


Carbohydrates as targeting compounds to produce infusions resembling espresso c...

Lopes, Guido R.; Passos, Cláudia P.; Petronilho, Sílvia; Rodrigues, Carla; Teixeira, J. A.; Coimbra, Manuel A.

All coffee brews are prepared with roasted coffee and water, giving origin to espresso, instant, or filtered coffee, exhibiting distinct physicochemical properties, depending on the extraction conditions. The different relative content of compounds in the brews modulates coffee body, aroma, and colour. In this study it was hypothesized that a coffee infusion allows to obtain extracts that resemble espresso coff...


Carbohydrates as targeting compounds to produce infusions resembling espresso c...

Lopes, Guido R.; Passos, Cláudia P.; Petronilho, Sílvia; Rodrigues, Carla; Teixeira, José A.; Coimbra, Manuel A.

All coffee brews are prepared with roasted coffee and water, giving origin to espresso, instant, or filtered coffee, exhibiting distinct physicochemical properties, depending on the extraction conditions. The different relative content of compounds in the brews modulates coffee body, aroma, and colour. In this study it was hypothesized that a coffee infusion allows to obtain extracts that resemble espresso coff...


In Vitro Hypocholesterolemic Effect of Coffee Compounds

Coreta-Gomes, Filipe Manuel; Lopes, Guido R.; Passos, Cláudia P.; Vaz, Inês M.; Machado, Fernanda; Geraldes, Carlos F. G. C.; Moreno, Maria João

(1) Background: Cholesterol bioaccessibility is an indicator of cholesterol that is available for absorption and therefore can be a measure of hypocholesterolemic potential. In this work, the effect of commercial espresso coffee and coffee extracts on cholesterol solubility are studied in an in vitro model composed by glycodeoxycholic bile salt, as a measure of its bioaccessibility. (2) Methods: Polysaccharide ...


Impact of microwave-assisted extraction on roasted coffee carbohydrates, caffei...

Lopes, Guido R.; Passos, Cláudia P.; Rodrigues, Carla; Teixeira, J. A.; Coimbra, Manuel A.

Microwave-assisted extraction (MAE) allows to quickly achieve soluble compounds from solid matrices due to the promotion of temperatures higher than the solvent (atmospheric) boiling point, once a closed-vessel system is used for operating at high pressure. In this study, the feasibility of MAE for producing high yield coffee extracts with properties that allow their commercial application was tested through a ...


Blanching impact on pigments, glucosinolates, and phenolics of dehydrated brocc...

Ferreira, Sónia S.; Monteiro, Filipa; Passos, Cláudia P.; Silva, Artur M. S.; Wessel, Dulcenia Ferreira; Coimbra, Manuel A.; Cardoso, Susana M.

Because of high water content, the valorisation of broccoli by-products requires dehydration that can preserve bioactive compounds. Blanching pre-treatment has been reported to improve the drying rate of broccoli. As a thermal treatment, it promotes also enzyme inactivation. Therefore, in this study, the impact of pre-dehydration blanching step, freeze-drying, air-drying at 40 °C, and microwave hydrodiffusion a...


Impact of microwave-assisted extraction on roasted coffee carbohydrates, caffei...

Lopes, Guido R.; Passos, Cláudia P.; Rodrigues, Carla; Teixeira, José A.; Coimbra, Manuel A.

Microwave-assisted extraction (MAE) allows to quickly achieve soluble compounds from solid matrices due to the promotion of temperatures higher than the solvent (atmospheric) boiling point, once a closed-vessel system is used for operating at high pressure. In this study, the feasibility of MAE for producing high yield coffee extracts with properties that allow their commercial application was tested through a ...


Apple Pomace Extract as a Sustainable Food Ingredient

Fernandes, Pedro A. R.; Ferreira, Sónia S.; Bastos, Rita; Ferreira, Isabel; Cruz, Maria T.; Pinto, António; Coelho, Elisabete; Passos, Cláudia P.

Apple pomace is a by-product of apple processing industries with low value and thus frequent disposal, although with valuable compounds. Acidified hot water extraction has been suggested as a clean, feasible, and easy approach for the recovery of polyphenols. This type of extraction allowed us to obtain 296 g of extract per kg of dry apple pomace, including 3.3 g of polyphenols and 281 g of carbohydrates. Ultra...


Modulation of infusion processes to obtain coffee-derived food ingredients with...

Lopes, Guido R.; Passos, Cláudia P.; Rodrigues, Carla; Teixeira, J. A.; Coimbra, Manuel A.

Coffee infusion experiments were conducted to infer how operational variables (time, temperature, mass to volume ratio, and grinding) might affect the efficiency and/or selectivity of compounds extraction. Although the different variables have extensively been reported independently, to the best of our knowledge, no experimental design was yet delineated to study the simultaneous effect of variables in coffee c...


Chemical composition and antimicrobial activity of Satureja montana byproducts ...

Santos, Jéssica D.C.; Coelho, Elisabete; Silva, Rita; Passos, Cláudia P.; Teixeira, Pedro; Henriques, Isabel; Coimbra, Manuel A.

Satureja montana is a worldwide consumed aromatic plant whose essential oils (EOs) are used as spice and preservative by food industry. Only the leaves are marketed, generating a large amount of stems as byproducts. It is possible that the EOs present in these byproducts represent a source of compounds with antimicrobial activity, as observed for the leaves. In this work, dried S. montana byproducts were used t...


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