3 documents found, page 1 of 1
Guidelines for prevention of febrile neutropenia.
Barroso, Sérgio; Damasceno, Margarida; Dinis, José; Gervásio, Helena; da Luz, Ricardo; Passos-Coelho, J L; Sá, Anabela; Costa, Luís; Rodrigues, HelenaNeutropenia and febrile neutropenia are common consequences of some cytotoxic chemotherapy regimens. This situation leads to modifications of the therapeutic regimen, conducting to either dose reduction or cycle delays. Granulocyte colony stimulating factors are commonly used to minimize chemotherapy cytotoxic effect on the granulocytic series. The objective of this study is to assess the available evidence in ...
The use of peripheral blood progenitor cells as an autologous hematopoietic sup...
Silva, M R; Passos-Coelho, J L; da Costa, F L; Machado, M A; Miranda, N; Miranda, M H; Parreira, AWe report the results of PBPC collection by large-volume leukaphereses and the hematologic recovery after high-dose chemotherapy supported by autologous PBPC reinfusion in a series of cancer patients treated at the Hematological Intensive Care Unit (UCHI) (Portuguese Institute of Oncology, Lisbon). Large volume leukaphereses were used to increase the efficacy of the PBPC collection. This modification of the sta...
The use of peripheral blood progenitor cells as an autologous hematopoietic sup...
Silva, M R; Passos-Coelho, J L; da Costa, F L; Machado, M A; Miranda, N; Miranda, M H; Parreira, AWe review the rationale for PBPC transplantation and the results reported in the literature. In order to prolong complete remissions and increase cure rates, high-dose chemotherapy is frequently used in the treatment of selected neoplasias. Hematological toxicity can be overcome by the infusion of autologous hemopoietic progenitors. Recently, peripheral blood is being used as the preferred source for hemopoieti...