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Editorial: Animal Poisoning and Biomarkers of Toxicity

Capela e Silva, Fernando; Sousa, A. C.; Pastorinho, M. Ramiro; Mizukawa, H.; Ishizuka, M

The worldwide incidence of animal poisoning is unknown. Despite reports pieced together by networks of veterinary clinics and poison control centers, their coverage is usually limited due to widespread under-reporting of cases (1–3). There are several reasons for this reality, being one of the major the wide gaps of knowledge regarding toxicosis agents and their profile (particularly in terms of toxicity mechan...


Ecotoxicity of plant extracts and essential oils: a review

Ferraz, C.; Palmeira de Oliveira, A.; Pastorinho, M. Ramiro; Sousa, Ana C.A.

Plant-based products such as essential oils and other extracts have been used for centuries due to their beneficial properties. Currently, their use is widely disseminated through a variety of industries and new applications are continuously emerging. For these reasons, they are produced industrially in large quantities and consequently they have the potential to reach the environment. However, the potential ef...


Chemical profile and eco-safety evaluation of essential oils and hydrolates fro...

Ferraz, C.; Sousa, Ana Catarina A.; Pastorinho, M. Ramiro

The demand for natural-based products for industrial applications is increasing sharply and therefore the search for new alternatives to the plants traditionally used is growing. These alternative plants can be an important source of bioactive compounds under a circular economy approach. Considering the potential future use of new plant products by the industry, it is necessary to assess the risk associated wit...


Burden of disease attributable to risk factors in European countries: a scoping...

Gorasso, Vanessa; Morgado, Joana Nazaré; Charalampous, Periklis; Pires, Sara M.; Haagsma, Juanita A.; Santos, João Vasco; Idavain, Jane; Ngwa, Che Henry

Objectives: Within the framework of the burden of disease (BoD) approach, disease, and injury burden estimates attributable to risk factors are a useful guide for policy formulation and priority setting in disease prevention. Considering the important differences in methods, and their impact on burden estimates, we conducted a scoping literature review to: (1) map the BoD assessments including risk factors perf...


Assessing exposure to environmental contaminants in portuguese mother-infant pa...

Namorado, Sónia; Pastorinho, M. Ramiro; Simões, Mariana; Coelho, Susana; Lamy, Elsa; Silva, Susana Pereira; Ogura, Joana; Nunes, Baltazar

Objective: Today chemicals play a major role in our daily lives, being present in the air we breathe, in the food we eat and in the products we use. As such, it is essential to know the levels of chemicals present in our bodies and assess the risks associated. For that, Human Biomonitoring (HBM), the measurement of the concentrations of chemicals in human biological samples, is a very useful technique. Neverthe...


Anticancer drugs in the environment: Environmental levels and technological cha...

Valente, João Vasco; Coelho, Susana; Pastorinho, M. Ramiro; Sousa, Ana Catarina A.

Cytostatic drugs are one of the most used therapeutic agents to treat cancer. However, their high toxicity turns their handling and disposal into a matter of great concern. Upon administration, cytostatics are mainly excreted through urine either as conjugated or unconjugated forms. The oncology patient’s urine enters sewage system, reaching wastewater treatment plants (WWTP) that are unable to remove cytostati...


Issue 1 - Update on adverse respiratory effects of outdoor air pollution. Part ...

Pastorinho, M. Ramiro; Sousa, Ana Catarina

Objective To analyse the GARD perspective on the health effects of outdoor air pollution, and to synthesise the Portuguese epidemiological contribution to knowledge on its respiratory impact. Results Ambient air pollution has deleterious respiratory effects which are more apparent in larger, densely populated and industrialised countries, such as Canada, Iran, Brazil and Portugal, but it also affects people liv...


Chemical profile and eco-safety evaluation of essential oils and hydrolates fro...

Ferraz, Celso Afonso; Sousa, Ana Catarina A.; Oliveira, Ana Palmeira de; Pastorinho, M. Ramiro; Caramelo, Débora; Delgado, F.M.G.

The demand for natural-based products for industrial applications is increasing sharply and therefore the search for new alternatives to the plants traditionally used is growing. These alternative plants can be an important source of bioactive compounds under a circular economy approach. Considering the potential future use of new plant extracts by the industry, it is necessary to assess the risk associated wit...


Chemical characterization and bioactive potential of Thymus × citriodorus (Pers...

Oliveira, Ana S.; Rolo, Joana; Gaspar, Carlos; Cavaleiro, Carlos; Salgueiro, Lígia; Palmeira-de-Oliveira, Rita; Ferraz, Celso; Coelho, Susana

Ethnopharmacological relevance: Thymus × citriodorus (Pers.) Schreb. is an interspecific hybrid between Thymus pulegioides and Thymus vulgaris, known for its pharmacological activities as diaphoretic, deodorant, antiseptic and disinfectant, the last mostly related with its antimicrobial activity. The folk use of other extracts, as hydrolates, have also been disseminated, as regulators of oily skin with anti-acn...


Mercury exposure in Portuguese adolescents

Namorado, Sónia; Gomes, Diogo; Iria, Diogo; Cestelli, Federico; Mota, Afonso; Alves, Bernardo; Leal, João; Luz, Andreia; Gomes, João; Barros, Rafael

The possible health effects related to exposure to hazardous chemicals have let to citizens interest in environmental health. Mercury, in particular, has been recognized as a chemical of concern, due to its well-known neurotoxicity and endocrine disrupting potential. In this work a group of teenagers from a school in Lisbon together with their teachers and researchers from the academia conducted a human biomoni...


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