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Issue 2 - "Update on adverse respiratory effects of indoor air pollution" Part ...

Cavaleiro Rufo, J; Annesi-Maesano, I; Carreiro-Martins, P; Moreira, A; Sousa, AC; Pastorinho, MR; Neuparth, N; Taborda-Barata, L

Objective To quantify the impact of different air pollutants on respiratory health based on robust estimates based on international data and to summarise the evidence of associations between indoor exposure to those pollutants and respiratory morbidity in the Portuguese population. Results Several systematic reviews and meta-analyses (MA) at the world level demonstrate the impact of indoor air quality on respir...


Issue 2 - “Update on adverse respiratory effects of indoor air pollution” Part ...

Rufo, JC; Annesi-Maesano, I; Carreiro-Martins, P; Moreira, A; Sousa, AC; Pastorinho, MR; Neuparth, N; Taborda-Barata, L

Objective To quantify the impact of different air pollutants on respiratory health based on robust estimates based on international data and to summarise the evidence of associations between indoor exposure to those pollutants and respiratory morbidity in the Portuguese population. Results Several systematic reviews and meta-analyses (MA) at the world level demonstrate the impact of indoor air quality on respir...


Burden of disease attributable to risk factors in European countries: a scoping...

Gorasso, V; Morgado, JN; Charalampous, P; Pires, SM; Haagsma, JA; Santos, JV; Idavain, J; Ngwa, CH; Noguer, I; Padron-Monedero, A; Sarmiento, R

Objectives Within the framework of the burden of disease (BoD) approach, disease and injury burden estimates attributable to risk factors are a useful guide for policy formulation and priority setting in disease prevention. Considering the important differences in methods, and their impact on burden estimates, we conducted a scoping literature review to: (1) map the BoD assessments including risk factors perfor...


Avaliação do potencial citotóxico de microplásticos em linhas celulares intesti...

Valente, JV; Cristóvão, AC; Pastorinho, MR; Sousa, ACA

Os Microplásticos (MPs) são uma classe emergente de contaminantes, que resultam da libertação directa de pequenas partículas que constituem total ou parcialmente objetos de uso quotidiano ou da deterioração de plásticos que originalmente possuem maiores dimensões. O polietileno (PE), a poliamida (PA-nylon 12) e o policloreto de vinilo (PVC) são três polímeros muito comumente utilizados no fabrico de sacos de pl...


Avaliação toxicológica de lixiviados de aterro sanitário tratados usando o crus...

Coelho, SR; Sousa, ACA; Pastorinho, MR; Pacheco, MJ; Ciríaco, L; Lopes, A; Fernandes, A

Os resíduos sólidos urbanos, gerados em grande escala pela sociedade moderna, precisam de ser corretamente descartados por forma a mitigar o seu impacto ambiental e na saúde pública. Estes resíduos são normalmente depositados em aterros sanitários, e, consequentemente, são gerados lixiviados altamente tóxicos que precisam de ser tratados. Este trabalho tem como objetivo avaliar a eficácia de diferentes tratamen...


When toxicity goes circular: Isoprostanes as markers and effectors of oxidative...

Pais, RT; Sousa, ACA; Pastorinho, MR

In normal conditions, there is a dynamic equilibrium between oxidants and antioxidants in the human body; however, when there is an unbalance in this redox state, oxidative stress occurs. In an unbalanced state, the peroxidation of polyunsaturated fatty acids originates isoprostanes (IsoPs), which can be considered as markers of oxidative stress. Since oxidative stress is associated with several non-communicabl...


Model for Health Risk Assessment in Portuguese Housing Spaces

Pastorinho, MR

Currently, people spend most of their time inside their homes. However, poor conditions in terms of comfort and quality of the indoor environment can pose high risks to the inhabitants’ health. Therefore, a good quality environment is essential, since, in addition to the hazards present in indoor air (e.g., particles, (S)VOCs, CO, radon and tobacco smoke), extreme temperatures, relative humidity levels, pests (...


Frailty syndrome, biomarkers and environmental factors – A pilot study

Pastorinho, MR; Sousa, ACA

Frailty is an age-related syndrome expected to increase over the next decades. This syndrome has been identified to be the most common condition leading to disability, institutionalisation and death in the elderly. The aim of this pilot study is to investigate a possible link between frailty status, biomarkers and environmental exposures. A group of 71 older adults (≥65 years old) was engaged in this study. The...


Ecotoxicological Evaluation of Methiocarb Electrochemical Oxidation

Pastorinho, MR; Sousa, ACA

The ecotoxicity of methiocarb aqueous solutions treated by electrochemical oxidation was evaluated utilizing the model organism Daphnia magna. The electrodegradation experiments were performed using a boron-doped diamond anode and the influence of the applied current density and the supporting electrolyte (NaCl or Na2SO4) on methiocarb degradation and toxicity reduction were assessed. Electrooxidation treatment...


Chemical characterization and bioactive potential of Thymus×citriodorus (Pers.)...

Oliveira, AS; Rolo, J; Gaspar, C; Cavaleiro, C; Salgueiro, L; Palmeira-de-Oliveira, R; Ferraz, C; Coelho, S; Pastorinho, MR; Sousa, AC; Teixeira, JP

Ethnopharmacological relevance: Thymus × citriodorus (Pers.) Schreb. is an interspecific hybrid between Thymus pulegioides and Thymus vulgaris, known for its pharmacological activities as diaphoretic, deodorant, antiseptic and disinfectant, the last mostly related with its antimicrobial activity. The folk use of other extracts, as hydrolates, have also been disseminated, as regulators of oily skin with anti-acn...


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