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Unclonable fluorescent tags produced on bioplastics by in-situ electron beam ir...

Calderon V, S.; Ballesteros, Lina F.; Gonçalves, C.; Dittmann, G.; Evans, C.; Cerqueira, Miguel A.; Pastrana, L. M.

Counterfeiting of assets, documents, and goods is a growing issue with substantial economic impacts from the proliferation of fake products and significant risks to consumer health and safety. This highlights the urgent need for advanced anti-counterfeiting technologies. In this work, we demonstrate a novel approach to creating unclonable fluorescent tags on poly(lactic acid) (PLA) films using electron beam irr...


Hydroxypropyl methylcellulose-based micro- and nanostructures for encapsulation...

Silva, Pedro Miguel Peixoto; Prieto, C.; Andrade, C. C. P.; Lagarón, J. M.; Pastrana, L. M.; Coimbra, M. A.; Vicente, A. A.

Electrohydrodynamic processing (EHDP) allows the use of a wide range of biopolymers and solvents, including food-grade biopolymers and green solvents, for the development of micro- and nanostructures. These structures present a high surface-area-to-volume ratio and different shapes and morphologies. The aim of this work was to design and produce hydroxypropyl methylcellulose (HPMC)-based micro- and nanostructur...


Hyaluronic acidamphotericin B nanocomplexes: a promising anti-leishmanial drug ...

Carvalho, Ricardo Emanuel Silva; Leão, T.; Bourbon, A. I.; Gonçalves, Catarina; Pastrana, L. M.; Parpot, Pier; Amorim, I.; Tomás, A. M.; Gama, F. M.

The development of an effective amphotericin B (AmB) formulation to replace actual treatments available for leishmaniasis, which present serious drawbacks, is a challenge. Here we report the development of hyaluronic acidamphotericin B self-assembled nanocomplexes (HAAmB), processed by freeze-drying (FD) or nano spray-drying (SD), using a simple process that favors the non-covalent drugpolysaccharide associatio...


Fungal growth and mycotoxin production in a new formulated meat product with st...

Guimarães, Ana Cristina Silva Esperança; Martins, A. J.; Cerqueira, M. A.; Pastrana, L. M.; Sousa, P.; Venâncio, Armando

One of the major changes in dietary habits of the last half-century has been the increase of meat-based products consumption. This increase has contributed to a diet rich in saturated fats, which can result in adverse health effects. A recent trend in food industry is the development of new meat products based on traditional ones, though having less saturated fats and adding healthy ingredients. In this work, t...


Food-grade hydroxypropyl methylcellulose-based formulations for electrohydrodyn...

Silva, Pedro; Prieto, C.; Lagarón, J. M.; Pastrana, L. M.; Coimbra, M. A.; Vicente, A. A.; Cerqueira, M. A.

Electrohydrodynamic (EHD) processing allows the production of micro and nano structures with high surface-area-to-volume ratio from biopolymers and environmentally friendly solvents. Such structures hold a very significant potential for application in the food area. The aim of this work was to assess the role of solution parameters in the formation of hydroxypropyl methylcellulose (HPMC)-based micro and nanostr...


Food grade polymers for the gelation of edible oils envisioning food applications

Martins, Artur J.; Pastrana, L. M.; Vicente, A. A.; Cerqueira, Miguel Ângelo Parente Ribeiro

Oleogels are systems traditionally produced by the self-assembly of materials called gelators, which are responsible for inducing viscosity and solid-like capabilities to oil-based systems. The emergent interest concerning oil structuring strategies in food applications is related to oleogels' capacity to undergo structural and textural tailoring, and the possibility of their use in delivery of bioactive compou...


Carbon-based sputtered coatings for enhanced chitosan-based films properties

Fernandes, C. P.; Velasco, Sebastian Calderon; Giraldo, Lina Fernanda Ballesteros; Cerqueira, Miguel A.; Pastrana, L. M.; Teixeira, J. A.

In order to make bio-based packaging materials competitive in comparison to petroleum-based one, some of their properties need to be improved, among which gas permeability is of crucial importance. Thus, in this work, carbon-based coatings were applied on chitosan-based films by radiofrequency reactive magnetron sputtering aiming to improve their barrier properties. Chemical and morphological properties were ev...


Development of antimicrobial leather modified with AgTiO2 nanoparticles for foo...

Carvalho, Isabel; Ferdov, S.; Mansilla, C.; Marques, S.; Cerqueira, M. A.; Pastrana, L. M.; Henriques, Mariana; Gaidau, C.; Ferreira, P.; Carvalho, S.

The proposed work aims to functionalize leathers for footwear industry with antimicrobial properties based on AgTiO2 nanoparticles. The synthesis of nanoparticles was carried out by the hydrothermal method with significant advantages in terms of time, energy savings and low cost. Anatase TiO2 nanoparticles with dimensions below 10nm were obtained as observed by X-ray diffraction and transmission electron micros...


Thermodynamic, rheological and structural properties of edible oils structured ...

Fasolin, Luiz H.; Cerqueira, Miguel Ângelo Parente Ribeiro; Pastrana, L. M.; Vicente, A. A.; Cunha, R. L.

The effect of different oil phases and low molecular weight organogelators (LMOGs) structures on edible oils was investigated through differential scanning calorimetry (DSC), rheology and small-angle X-ray scattering (SAXS). Different gelators (glyceryl tristearateGT; sorbitan tristearateST; sorbitan monostearateSM and glyceryl monostearate-GM) were tested in medium-chain triglycerides and high oleic sunflower ...


Development of antimicrobial leather modified with Ag-TiO2 nanoparticles for fo...

Carvalho, Isabel; Ferdov, S.; Cerqueira, M. A.; Pastrana, L. M.; Henriques, Mariana; Gaidau, C.; Carvalho, S.

[Excerpt] The proposed work aims to functionalize leathers for footwear industry with antimicrobial properties based on Ag-TiO2 nanoparticles. The synthesis of nanoparticles was carried out through an innovative and optimized method. This hydrothermal method is simple and inexpensive and prepares well crystalline materials. The structural characteristics were evaluated by X-ray powder diffraction and the result...


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