2 documents found, page 1 of 1
Consequences of the variability of the CovRS and RopB regulators among Streptoc...
Friães, Ana; Pato, Catarina; Cristino, José Melo; Ramirez, MárioTo evaluate the importance of covRS and ropB mutations in invasive disease caused by Group A Streptococci (GAS), we determined the sequence of the covRS and ropB genes of 191 isolates from invasive infections and pharyngitis, comprising a diverse set of emm types and multilocus sequence types. The production of SpeB and the activity of NAD glycohydrolase (NADase) and streptolysin S (SLS) were evaluated. The res...
Emergence of the same successful clade among distinct populations of emm89 Stre...
Friães, Ana; Machado, Miguel P.; Pato, Catarina; Carrico, Joao Andre; Cristino, José Melo; Ramirez, MárioThe emergence of clades within emm89 Streptococcus pyogenes isolates that rapidly became the dominant lineages expressing this emm type was recently reported in the United Kingdom and in a study that included isolates from the United States, Finland, and Iceland (United States/FI/IC). In the United Kingdom, the emerging clade was associated with the absence of the hasABC locus, responsible for the synthesis of ...