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Applied nanotechnologies in anticoagulant therapy: from anticoagulants to coagu...

Patriota, Yuri B. G.; Chaves, Luíse L.; Gocke, Evren H.; Severino, Patricia; Soares, Mônica F. R.; Soares-Sobrinho, José L.; Souto, Eliana B.

Heparin-based delivery systems have been explored to improve their therapeutic efficacy and to reduce toxicity for different administration routes. Regardless of the applied drug delivery system (DDS), the evaluation of anticoagulant performance is instrumental for the development of a suitable DDS. The understanding of the range of anticoagulant assays, together with their key applications and limitations, is ...


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