15 documents found, page 1 of 2
Methylene blue associated with maghemite nanoparticles has antitumor activity i...
Silva, Ana Luísa G.; Carvalho, Natália V.; Paterno, Leonardo Giordano; Moura, Ludmilla David de; Filomeno, Cleber Lopes; Paula, Eneida deBackground: Cancer constitutes group of diseases responsible for the second largest cause of global death, and it is currently considered one of the main public health concerns nowadays. Early diagnosis associated with the best choice of therapeutic strategy, is essential to achieve success in cancer treatment. In women, breast cancer is the second most common type, whereas ovarian cancer has the highest lethal...
Extracellular vesicles in infectious diseases caused by protozoan parasites in ...
Pontes, Leticia Gomes de [UNESP]; Altei, Wanessa Fernanda; Galan, Asier; Bilic, Petra; Guillemin, Nicolas; Kules, Josipa; Horvatic, AnitaMade available in DSpace on 2020-12-10T20:01:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-05-29. Added 1 bitstream(s) on 2021-07-15T15:25:05Z : No. of bitstreams: 1 S1678-91992020000100314.pdf: 5541148 bytes, checksum: 0557e47fe298c3fd72e9ef0243fc3ca6 (MD5); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenaç...
Influence of chitosan-tripolyphosphate nanoparticles on thermosensitive polymer...
Freitas Mariano, Kelli C.; Monteiro do Nascimento, Monica H.; Querobino, Samyr M.; Ramos Campos, Estefania [UNESP]; Oliveira, Jhones L. de [UNESP]Made available in DSpace on 2019-10-04T12:37:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-04-04; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundacao de Amparoa Pesquisa do Estado de Sao Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Chitosan-tripolyphosphate (CS-TPP) nanoparticles containing naproxen (NPX) were dispersed in poloxamer (PL) as u...
Acmella oleracea and Achyrocline satureioides as Sources of Natural Products in...
Yamane, Lais Thiemi; Paula, Eneida de; Jorge, Michelle Pedroza; Freitas-Blanco, Veronica Santana de; Montanari Junior, Ilio; Figueira, Glyn MaraMade available in DSpace on 2018-11-26T17:06:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-01-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The Brazilian forests have one of the world's biggest biodiversities. Achyrocline satureioides (macela) and Acmella oleracea (jambu) are native species from Brazil with a huge therapeutic potential, with proved anti-inflammatory and anesthet...
Development of egg PC/cholesterol/alpha-tocopherol liposomes with ionic gradien...
Goncalves da Silva, Camila Morais; Fraceto, Leonardo Fernandes [UNESP]; Franz-Montan, Michelle; Couto, Veronica Muniz; Casadei, Bruna RenataMade available in DSpace on 2018-11-26T16:19:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-01-02; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Context: Ropivacaine (RVC) is an aminoamide local anesthetic widely used in surgical procedures. Studies with RVC encapsulated in liposomes and complexed in cyclodextrins have shown good results, but in order to use RVC for lengthy procedure...
Budesonide-hydroxypropyl-beta-cyclodextrin inclusion complex in binary poloxame...
Santos Akkari, Alessandra Cristina; Ramos Campos, Estefania Vangelie [UNESP]; Keppler, Artur Franz; Fraceto, Leonardo Fernandes [UNESP]Made available in DSpace on 2018-11-27T07:08:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-02-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundacao de Amparo Pesquisa do Estado de Sao Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Budesonide (BUD) is a glucocorticoid widely used for the treatment of ulcerative colitis. In this work, we propos...
Benzocaine complexation with p-sulfonic acid calix[n]arene: experimental (1 H-N...
Arantes, Lucas M.; Varejão, Eduardo V. V.; Pelizzaro-Rocha, Karin J.; Cereda, Cíntia M. S.; Paula, Eneida de; Lourenço, Maicon P.; Duarte, Hélio A.The aim of this work was to study the interaction between the local anesthetic benzocaine and p-sulfonic acid calix[n]arenes using NMR and theoretical calculations and to assess the effects of complexation on cytotoxicity of benzocaine. The architectures of the complexes were proposed according to (1) H NMR data (Job plot, binding constants, and ROESY) indicating details on the insertion of benzocaine in the ca...
Delivery system for mefenamic acid based on the nanocarrier layered double hydr...
Cunha, Vanessa R. R.; Guilherme, Viviane A.; Paula, Eneida de; Araujo, Daniele R. de; Silva, Renan O.; Medeiros, Jand V. R.; Leite, José R. S. A.Purpose The anionic form of the drug mefenamic acid intercalated into the nanocarrier layered double hydroxide (LDH-Mef) was evaluated by anti-inflammatory and antinociceptive assays. Methods The LDH-Mef material was characterized by a set of physicochemical techniques, which was supported by Density Functional Theory calculations. The pharmacological effects of LDH-Mef (40 wt% of drug) were evaluated by hemoly...
Proparacaine complexation with β-cyclodextrin and p-sulfonic acid calix[6]arene...
Arantes, Lucas Micquéias; Scarelli, Camilla; Marsaioli, Anita Jocelyne; Paula, Eneida de; Fernandes, Sergio AntonioThis study focused on the use of NMR techniques as a tool for the investigation of complex formation between proparacaine and cyclodextrins (CDs) or p-sulfonic acid calix[6]arene. The pH dependence of the complexation of proparacaine with β-CD and p-sulfonic acid calix[6]arene was studied and binding constants were determined by 1H NMR spectroscopy [diffusion-ordered spectroscopy (DOSY)] for the charged and unc...
Desenvolvimento e caracterização de nanocápsulas de poli(l-lactídeo) contendo b...
Melo, Nathalie Ferreira Silva de [UNESP]; Grillo, Renato [UNESP]; Fraceto, Leonardo Fernandes [UNESP]; Dias Filho, Newton Luiz [UNESP]; Paula, Eneida deMade available in DSpace on 2015-05-15T13:30:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2010Bitstream added on 2015-05-15T13:56:28Z : No. of bitstreams: 1 ISSN0100-4042-2010-33-01-65-69.pdf: 301580 bytes, checksum: c49b2e5ea5d0c8210c7e7d88feaf2818 (MD5); In this paper we describe the preparation poly (L-lactide) (PLA) nanocapsules as a drug delivery system for the local anesthetic benzocaine. The char...