The Western-blotting technique was applied to identify antigenic fractions of excretory-secretory Toxocara canis antigen recognized by IgG antibodies throughout an experimental infection in mice challenged by different inocula. Mice were inoculated with 5, 50 and 500 embryonated eggs and serum samples were collected 15, 30, 60, 90 and 120 days post-infection. Serum samples were analyzed using an excretory-secre...
Approximately 240 million people worldwide are infected by Schistosoma. In Brazil, one of the main intermediate hosts of this parasite is Biomphalaria glabrata snails. The early detection of larval stages in intermediate hosts is an important challenge to public health, but it also represents an opportunity as a new alternative to indicate earlier natural infections before cercariae differentiation and emergenc...
In experimental infection with Strongyloides venezuelensis, the acute and recovery phases can be distinguished, unlike human infections caused by Strongyloides stercoralis. The objective of this study was to evaluate the production of anti-Strongyloides IgG antibodies and the recognition of immunogenic protein bands during the acute and the recovery phases in rats experimentally infected with S. venezuelensis. ...
A estrongiloidíase é uma doença parasitária resultante da infecção pelo Strongyloides stercoralis que pode evoluir para hiperinfecção, principalmente em indivíduos imunodeprimidos. Considerando que Uberlândia é uma região hiperendêmica para este geo-helminto propõe-se realizar e comparar os diagnósticos parasitológico e imunológico da estrongiloidíase em 151 crianças sendo 68 imunocompetentes (IC) e 83 imunodep...
ABSTRACTThe main aspects and problems related to laboratory diagnosis of the human infection by Strongyloides stercoralis, especially in the case of immunocompromised patients, are discussed. The perspectives for improving the performance of diagnostic tests are also appointed. Keywords: Strongyloidiasis, Clinical laboratory techniques, Patients, Immunocompromised hostsRESUMOO presente artigo discute os princip...
Trabalho de Conclusão de Curso (Graduação); Procedeu-se a pesquisa de parasitas e comensais intestinais em amostras de fezes colhidas de 110 crianças de 0 a 12 anos de idade internadas na enfermaria de Pediatria do Hospital de Clínicas da Universidade Federal de Uberlândia. Das 110 crianças, 80 pertenciam aos imunocompetentes e 30 ao imunodeprimidos (por corticoides, leucemias, tumores, subnutrição ou doenças i...
Orientadores: Vanderlei Rodrigues, Marlene Tiduko Ueta; Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia; Resumo: As proteases, sobretudo os complexos enzimáticos como o proteassoma 26S, têm sido relacionadas com diferentes processos biológicos em parasitas. O presente trabalho, teve como objetivo realizar um estudo inicial do proteassoma 26S no nematódeo Strongyloides venezuelensis, ...