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p-Methoxycinnamic acid diesters lower dyslipidemia, liver oxidative stress and ...

Paim, Raquel Teixeira Terceiro; Rodrigues, Paula Salmito Alves; Silva, José Ytalo Gomes da; Paula Junior, Valdir Ferreira de; Silva, Bruno Bezerra da

The pursuit of cholesterol lowering natural products with less side e ects is needed for controlling dyslipidemia and reducing the increasing toll of cardiovascular diseases that are associated with morbidity and mortality worldwide. The present study aimed at the examining e ects of p-methoxycinnamic acid diesters (PCO-C) from carnauba (Copernicia prunifera)-derived wax on cytotoxic, genotoxic responses in vit...

Date: 2020   |   Origin: Oasisbr

Chemical composition and antifungal In vitro and in silico, antioxidant, and an...

Nascimento, José Eranildo Teles do; Rodrigues, Ana LivyaMoreira; Lisboa, Daniele Silva de; Liberato, Hortência Ribeiro; Falcão, Maria José Cajazeiras

Ouratea fieldingiana (Gardner) Engl is popularly used for wound healing. This study describes the main chemical compounds present in extracts of O. fieldingiana and evaluates their biological potential by investigating antifungal, antioxidant, and anticholinesterase activities.The actionmechanismofmain antifungal compound was investigated bymolecular docking using the enzyme sterol 14- demethylase, CYP51, requi...

Date: 2019   |   Origin: Oasisbr

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