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Dipeptidyl Peptidase-4 Is a Pro-Recovery Mediator During Acute Hepatotoxic Dama...

Duarte, Nádia; Coelho, Inês; Holovanchuk, Denys; Inês Almeida, Joana; Penha-Gonçalves, Carlos; Paula Macedo, Maria

Dipeptidyl peptidase-4 (DPP-4 or clusters of differentiation [CD]26) is a multifunctional molecule with established roles in metabolism. Pharmacologic inhibition of DPP-4 is widely used to improve glycemic control through regulation of the incretin effect. Colaterally, CD26/DPP-4 inhibition appears to be beneficial in many inflammatory conditions, namely in delaying progression of liver pathology. Nevertheless,...

Date: 2018   |   Origin: Repositório Institucional da UNL
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