Abstract Aim: The preventive and therapeutic role of physical exercise in Parkinson’s disease (PD) has been the target of study of many scientific groups, and the research often is done in experimental models, especially rodents. Thus, the aim of this review was to analyze a database, elucidating the main benefits that the systematized practice of physical activity/ exercises can contribute to PD in animal mode...
ABSTRACT Objective To investigate the effects of physical training on metabolic and morphological parameters of diabetic rats. Methods Wistar rats were randomized into four groups: sedentary control, trained control, sedentary diabetic and trained diabetic. Diabetes mellitus was induced by Alloxan (35mg/kg) administration for sedentary diabetic and Trained Diabetic Groups. The exercise protocol consisted of swi...
Abstract Epidemiological studies indicate continuous increases in the prevalence of Alzheimer’s Disease (AD) in the next few decades. The key feature of this disease is hippocampal neurodegeneration. This structure has an important role in learning and memory. Intense research efforts have sought to elucidate neuroprotective mechanisms responsible for hippocampal integrity. Insulin signaling seems to be a very ...
Abstract Glucose uptake is an important phenomenon for cell homeostasis and for organism health. Under resting conditions, skeletal muscle is dependent on insulin to promote glucose uptake.Insulin, after binding to its membrane receptor, triggers a cascade of intracellular reactions culminating in activation of the glucose transporter 4, GLUT4, among other outcomes.This transporter migrates to the plasma membra...
RESUMOO Objetivo deste estudo foi investigar os efeitos de diferentes protocolos de treinamento físico (TF) sobre a sensibilidade à insulina (SI) e a fosforilação da Akt (p-Akt) no músculo de ratos obesos. Os animais foram distribuídos em quatro grupos: Controle: recebeu dieta padrão (C); Obeso sedentário: recebeu dieta hiperlipídica (DHL) por 12 semanas (OS); Obeso treinado-1: recebeu DHL por 12 semanas e TF s...
Objective : To investigate the effects of different intensities of acute exercise on insulin sensitivity and protein kinase B/Akt activity in skeletal muscle of obese mice. Methods : Swiss mice were randomly divided into four groups, and fed either a standard diet (control group) or high fat diet (obese sedentary group and obese exercise group 1 and 2) for 12 weeks. Two different exercise protocols were used: s...
ObjectiveTo investigate the effects of a specific protocol of undulatory physical resistance training on maximal strength gains in elderly type 2 diabetics.Methods The study included 48 subjects, aged between 60 and 85 years, of both genders. They were divided into two groups: Untrained Diabetic Elderly (n=19) with those who were not subjected to physical training and Trained Diabetic Elderly (n=29), with those...
<p><b>OBJECTIVE:</b> Investigation of effects of supervised resistance training program on functional fitness in elderly type 2 diabetic patients.<br> <b>MATERIAL AND METHODS:</b> The study included 51 patients from both genders, aged between 60 and 80 years old, diagnosed with type 2 diabetes. Measurement of body mass index (IMC), waist circumference (PC) and hip circumference (PQ) was evaluated according to p...
OBJETIVO: O presente estudo teve como objetivo analisar as alterações bioquímicas hepáticas decorrentes da administração de uma dieta hiperlipídica/hiperenergética em ratos. MÉTODOS: Foram utilizados 20 ratos (Wistar) com 90 dias de idade divididos em dois grupos, grupo-controle constituída por ratos eutróficos alimentados com dieta comercial para roedores e grupo-dieta constituída por ratos submetidos a uma di...
INTRODUÇÃO: A carência de valores de referência de parâmetros antropométricos, de desempenho, bioquímicos, hematológicos, hormonais e psicológicos é uma limitação importante nas investigações envolvendo futebolistas profissionais. OBJETIVO: Elaborar tabelas de percentis para servirem como referencial de comparação para estudos posteriores. MÉTODOS: Foram utilizados 82 jogadores profissionais de futebol que fora...